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Gene: DAB2 (DAB adaptor protein 2) Homo sapiens
Symbol: DAB2
Name: DAB adaptor protein 2
Description: Exhibits several functions, including SMAD binding activity; clathrin adaptor activity; and protein C-terminus binding activity. Involved in several processes, including regulation of signal transduction; regulation of transcription, DNA-templated; and regulation of vesicle-mediated transport. Localizes to several cellular components, including the clathrin-coated pit; clathrin-coated vesicle; and fibrillar center.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adaptor molecule disabled-2; Dab, mitogen-responsive phosphoprotein, homolog 2; Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila); differentially expressed in ovarian carcinoma 2; differentially-expressed protein 2; disabled homolog 2; disabled homolog 2, mitogen-responsive phosphoprotein; DOC-2; DOC2; FLJ26626; mitogen-responsive phosphoprotein
Mus musculus (house mouse) : Dab2 (disabled 2, mitogen-responsive phosphoprotein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dab2 (DAB adaptor protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dab2 (DAB adaptor protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DAB2 (DAB adaptor protein 2)
Canis lupus familiaris (dog) : DAB2 (DAB adaptor protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dab2 (DAB adaptor protein 2)
Sus scrofa (pig) : DAB2 (DAB adaptor protein 2)
Chlorocebus sabaeus (African green monkey) : DAB2 (DAB adaptor protein 2)
Heterocephalus glaber (naked mole-rat) : Dab2 (DAB adaptor protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl539,371,675 - 39,462,300 (-)EnsemblGRCh38hg38GRCh38
GRCh38539,371,674 - 39,425,233 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37539,371,776 - 39,425,335 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36539,407,537 - 39,461,092 (-)NCBINCBI36hg18NCBI36
Build 34539,408,502 - 39,460,703NCBI
Celera539,258,704 - 39,312,863 (-)NCBI
Cytogenetic Map5p13.1NCBI
HuRef539,323,383 - 39,377,010 (-)NCBIHuRef
CHM1_1539,373,679 - 39,427,330 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DAB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731451
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.