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Gene: Myo5a (myosin VA) Mus musculus
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Symbol: Myo5a
Name: myosin VA
Description: Exhibits several functions, including Rab GTPase binding activity; calmodulin binding activity; and disordered domain specific binding activity. Involved in several processes, including establishment of endoplasmic reticulum localization to postsynapse; melanosome transport; and secretion by cell. Localizes to several cellular components, including the cytoplasmic vesicle; cytoskeleton; and photoreceptor outer segment. Colocalizes with the microtubule plus-end. Used to study Griscelli syndrome type 1. Human ortholog(s) of this gene implicated in Griscelli syndrome type 1. Is expressed in central nervous system; peripheral nervous system ganglion; and retina. Orthologous to human MYO5A (myosin VA); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9630007J19Rik; AI413174; AI661011; d; d-120J; Dbv; dilute lethal-20J protein; dilute myosin heavy chain, non-muscle; flail; flailer; flr; MVa; Myo5; myosin-Va; MyoVA; Sev-1; unconventional myosin-Va
Orthologs:
Homo sapiens (human) : MYO5A (myosin VA)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myo5a (myosin VA)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myo5a (myosin VA)
Pan paniscus (bonobo/pygmy chimpanzee) : MYO5A (myosin VA)
Canis lupus familiaris (dog) : MYO5A (myosin VA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myo5a (myosin VA)
Sus scrofa (pig) : MYO5A (myosin VA)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38975,069,799 - 75,223,688 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37974,919,013 - 75,071,495 (+)NCBIGRCm37mm9NCBIm37
MGSCv36974,858,205 - 75,005,381 (+)NCBImm8
Celera972,225,104 - 72,382,491 (+)NCBICelera
Cytogenetic Map9 DNCBI
cM Map942.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Myo5a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731454
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.