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Gene: STX4 (syntaxin 4) Homo sapiens
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Symbol: STX4
Name: syntaxin 4
Description: Exhibits sphingomyelin phosphodiesterase activator activity. Involved in several processes, including long-term synaptic potentiation; positive regulation of cellular protein localization; and positive regulation of secretion by cell. Localizes to several cellular components, including the basolateral plasma membrane; cytoplasmic vesicle; and glutamatergic synapse; PARTICIPATES IN E-cadherin signaling pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: p35-2; renal carcinoma antigen NY-REN-31; STX4A; syntaxin 4A (placental); syntaxin-4
Orthologs:
Mus musculus (house mouse) : Stx4a (syntaxin 4A (placental))  MGI  Alliance
Rattus norvegicus (Norway rat) : Stx4 (syntaxin 4)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : STX4 (syntaxin 4)
Canis lupus familiaris (dog) : STX4 (syntaxin 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stx4 (syntaxin 4)
Sus scrofa (pig) : STX4 (syntaxin 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381631,033,095 - 31,040,168 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371631,044,416 - 31,051,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,952,404 - 30,958,986 (+)NCBINCBI36hg18NCBI36
Build 341630,952,403 - 30,958,985NCBI
Celera1629,246,015 - 29,253,171 (-)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1628,606,302 - 28,613,331 (+)NCBIHuRef
CHM1_11632,361,656 - 32,368,735 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on STX4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731468
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.