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Gene: SH3BP4 (SH3 domain binding protein 4) Homo sapiens
Symbol: SH3BP4
Name: SH3 domain binding protein 4
Description: Exhibits GDP-dissociation inhibitor activity; Ras GTPase binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of GTPase activity; negative regulation of TOR signaling; and protein localization to lysosome. Localizes to the cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BOG25; EH-binding protein 10; SH3 domain-binding protein 4; SH3-domain binding protein 4; transferrin receptor trafficking protein; transferrin receptor-trafficking protein; TTP
Mus musculus (house mouse) : Sh3bp4 (SH3-domain binding protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sh3bp4 (SH3-domain binding protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3bp4 (SH3 domain binding protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3BP4 (SH3 domain binding protein 4)
Canis lupus familiaris (dog) : SH3BP4 (SH3 domain binding protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3bp4 (SH3 domain binding protein 4)
Sus scrofa (pig) : SH3BP4 (SH3 domain binding protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2234,952,017 - 235,055,714 (+)Ensembl
GRCh382234,952,017 - 235,055,714 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372235,860,628 - 235,964,358 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,525,367 - 235,629,097 (+)NCBINCBI36hg18NCBI36
Build 342235,642,685 - 235,746,356NCBI
Celera2229,577,847 - 229,681,460 (+)NCBI
Cytogenetic Map2q37.2NCBI
HuRef2227,700,099 - 227,760,480 (+)NCBIHuRef
CHM1_12235,866,502 - 235,970,051 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SH3BP4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731485
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.