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Gene: Cdc25a (cell division cycle 25A) Mus musculus
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Symbol: Cdc25a
Name: cell division cycle 25A
Description: Predicted to have chaperone binding activity; protein kinase binding activity; and protein tyrosine phosphatase activity. Predicted to be involved in cellular response to UV; mitotic cell cycle phase transition; and positive regulation of cell cycle G2/M phase transition. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease; cervical cancer; prostate cancer; and urinary bladder cancer. Is expressed in several structures, including adrenal gland; central nervous system; gonad; gut; and thymus. Orthologous to human CDC25A (cell division cycle 25A); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D9Ertd393e; dual specificity phosphatase Cdc25A; M-phase inducer phosphatase 1
Orthologs:
Homo sapiens (human) : CDC25A (cell division cycle 25A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdc25a (cell division cycle 25A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc25a (cell division cycle 25A)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC25A (cell division cycle 25A)
Canis lupus familiaris (dog) : CDC25A (cell division cycle 25A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc25a (cell division cycle 25A)
Sus scrofa (pig) : CDC25A (cell division cycle 25A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389109,875,518 - 109,893,895 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379109,778,083 - 109,796,394 (+)NCBIGRCm37mm9NCBIm37
MGSCv369109,733,366 - 109,751,296 (+)NCBImm8
Celera9109,601,935 - 109,621,511 (+)NCBICelera
Cytogenetic Map9 F2NCBI
cM Map959.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Cdc25a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731493
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.