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Gene: PRDX4 (peroxiredoxin 4) Homo sapiens
Symbol: PRDX4
Name: peroxiredoxin 4
CRRD ID: 731497
Description: Predicted to have identical protein binding activity and thioredoxin peroxidase activity. Predicted to be involved in cell redox homeostasis and response to oxidative stress. Localizes to extracellular exosome and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antioxidant enzyme AOE372; AOE37-2; AOE372; epididymis secretory sperm binding protein Li 97n; HEL-S-97n; peroxiredoxin IV; peroxiredoxin-4; PRX-4; prx-IV; thioredoxin peroxidase (antioxidant enzyme); thioredoxin peroxidase AO372; thioredoxin-dependent peroxide reductase A0372; thioredoxin-dependent peroxiredoxin 4
Mus musculus (house mouse) : Prdx4 (peroxiredoxin 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prdx4 (peroxiredoxin 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prdx4 (peroxiredoxin 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PRDX4 (peroxiredoxin 4)
Canis lupus familiaris (dog) : PRDX4 (peroxiredoxin 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prdx4 (peroxiredoxin 4)
Sus scrofa (pig) : PRDX4 (peroxiredoxin 4)
Chlorocebus sabaeus (African green monkey) : PRDX4 (peroxiredoxin 4)
Heterocephalus glaber (naked mole-rat) : Prdx4 (peroxiredoxin 4)
more info ...
Related Pseudogenes: PRDX4P1   PRDX4P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 EnsemblX23,664,262 - 23,686,397 (+)EnsemblGRCh38hg38GRCh38
GRCh38X23,667,493 - 23,686,397 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X23,682,377 - 23,704,516 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X23,595,566 - 23,614,435 (+)NCBINCBI36hg18NCBI36
Build 34X23,445,301 - 23,464,171NCBI
CeleraX27,807,255 - 27,826,109 (+)NCBI
Cytogenetic MapXp22.11NCBI
HuRefX21,425,714 - 21,444,033 (+)NCBIHuRef
CHM1_1X23,716,633 - 23,735,478 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PRDX4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731497
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.