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Gene: SERPINI1 (serpin family I member 1) Homo sapiens
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Symbol: SERPINI1
Name: serpin family I member 1
Description: Exhibits serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity and positive regulation of neuron projection development. Localizes to the cytoplasmic vesicle lumen; extracellular space; and neuronal cell body. Implicated in familial encephalopathy with neuroserpin inclusion bodies.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp781N13156; neuroserpin; peptidase inhibitor 12; PI-12; PI12; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1
Orthologs:
Mus musculus (house mouse) : Serpini1 (serine (or cysteine) peptidase inhibitor, clade I, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Serpini1 (serpin family I member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpini1 (serpin family I member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINI1 (serpin family I member 1)
Canis lupus familiaris (dog) : SERPINI1 (serpin family I member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpini1 (serpin family I member 1)
Sus scrofa (pig) : SERPINI1 (serpin family I member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383167,735,644 - 167,825,569 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373167,453,432 - 167,543,357 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363168,936,217 - 169,026,048 (+)NCBINCBI36hg18NCBI36
Build 343168,936,224 - 169,026,056NCBI
Celera3165,851,868 - 165,941,800 (+)NCBI
Cytogenetic Map3q26.1NCBI
HuRef3164,823,494 - 164,913,496 (+)NCBIHuRef
CHM1_13167,416,304 - 167,506,237 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SERPINI1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731505
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.