Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SERPINI1 (serpin family I member 1) Homo sapiens
Symbol: SERPINI1
Name: serpin family I member 1
Description: Exhibits serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity and positive regulation of neuron projection development. Localizes to the cytoplasmic vesicle lumen; extracellular space; and neuronal cell body. Implicated in familial encephalopathy with neuroserpin inclusion bodies.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp781N13156; neuroserpin; peptidase inhibitor 12; PI-12; PI12; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1
Mus musculus (house mouse) : Serpini1 (serine (or cysteine) peptidase inhibitor, clade I, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Serpini1 (serpin family I member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpini1 (serpin family I member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINI1 (serpin family I member 1)
Canis lupus familiaris (dog) : SERPINI1 (serpin family I member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpini1 (serpin family I member 1)
Sus scrofa (pig) : SERPINI1 (serpin family I member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh383167,735,644 - 167,825,569 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373167,453,432 - 167,543,357 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363168,936,217 - 169,026,048 (+)NCBINCBI36hg18NCBI36
Build 343168,936,224 - 169,026,056NCBI
Celera3165,851,868 - 165,941,800 (+)NCBI
Cytogenetic Map3q26.1NCBI
HuRef3164,823,494 - 164,913,496 (+)NCBIHuRef
CHM1_13167,416,304 - 167,506,237 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SERPINI1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731505
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.