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Gene: NOX4 (NADPH oxidase 4) Homo sapiens
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Symbol: NOX4
Name: NADPH oxidase 4
Description: Exhibits modified amino acid binding activity. Involved in several processes, including heart process; homocysteine metabolic process; and superoxide metabolic process. Localizes to the nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: kidney oxidase-1; kidney superoxide-producing NADPH oxidase; KOX; KOX-1; renal NAD(P)H-oxidase; RENOX
Orthologs:
Mus musculus (house mouse) : Nox4 (NADPH oxidase 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nox4 (NADPH oxidase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nox4 (NADPH oxidase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : NOX4 (NADPH oxidase 4)
Canis lupus familiaris (dog) : NOX4 (NADPH oxidase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nox4 (NADPH oxidase 4)
Sus scrofa (pig) : NOX4 (NADPH oxidase 4)
Chlorocebus sabaeus (African green monkey) : NOX4 (NADPH oxidase 4)
Heterocephalus glaber (naked mole-rat) : Nox4 (NADPH oxidase 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1189,324,353 - 89,498,187 (-)EnsemblGRCh38hg38GRCh38
GRCh381189,324,353 - 89,589,557 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371189,057,521 - 89,322,779 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361188,699,160 - 88,864,301 (-)NCBINCBI36hg18NCBI36
Build 341188,699,159 - 88,864,301NCBI
Celera1185,399,612 - 85,574,418 (+)NCBI
Cytogenetic Map11q14.3NCBI
HuRef1185,294,642 - 85,559,923 (-)NCBIHuRef
CHM1_11188,940,465 - 89,205,767 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NOX4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731542
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.