Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: EIF2B5 (eukaryotic translation initiation factor 2B subunit epsilon) Homo sapiens
Analyze
Symbol: EIF2B5
Name: eukaryotic translation initiation factor 2B subunit epsilon
Description: Contributes to guanyl-nucleotide exchange factor activity and translation initiation factor activity. Involved in several processes, including T cell receptor signaling pathway; glial cell development; and translational initiation. Localizes to the cytosol and eukaryotic translation initiation factor 2B complex. Implicated in leukoencephalopathy with vanishing white matter.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CACH; CLE; EIF-2B; eIF-2B GDP-GTP exchange factor subunit epsilon; EIF2Bepsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; initiation factor eif-2be; LVWM; translation initiation factor eIF-2B subunit epsilon
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,135,023 - 184,145,311 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373183,852,810 - 183,863,099 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,335,504 - 185,345,793 (+)NCBINCBI36hg18NCBI36
Build 343185,335,825 - 185,345,792NCBI
Celera3182,295,251 - 182,305,538 (+)NCBI
Cytogenetic Map3q27.1NCBI
HuRef3181,260,682 - 181,271,225 (+)NCBIHuRef
CHM1_13183,817,213 - 183,827,502 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on EIF2B5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731553
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.