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Gene: Xylt2 (xylosyltransferase II) Mus musculus
Symbol: Xylt2
Name: xylosyltransferase II
Description: Predicted to have magnesium ion binding activity; manganese ion binding activity; and protein xylosyltransferase activity. Involved in heparin biosynthetic process and proteoglycan biosynthetic process. Predicted to localize to extracellular space. Used to study polycystic kidney disease. Human ortholog(s) of this gene implicated in pseudoxanthoma elasticum. Is expressed in alimentary system; cardiovascular system; integumental system; and nervous system. Orthologous to human XYLT2 (xylosyltransferase 2); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; heparan sulfate biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; succimer; (+)-schisandrin B (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E030002B02Rik; peptide O-xylosyltransferase 2; XT-II; XT2; xylosyltransferase 2; xylT-II
Homo sapiens (human) : XYLT2 (xylosyltransferase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Xylt2 (xylosyltransferase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xylt2 (xylosyltransferase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : XYLT2 (xylosyltransferase 2)
Canis lupus familiaris (dog) : XYLT2 (xylosyltransferase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xylt2 (xylosyltransferase 2)
Sus scrofa (pig) : XYLT2 (xylosyltransferase 2)
Chlorocebus sabaeus (African green monkey) : XYLT2 (xylosyltransferase 2)
Heterocephalus glaber (naked mole-rat) : Xylt2 (xylosyltransferase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1194,663,851 - 94,677,515 (-)EnsemblGRCm38mm10GRCm38
GRCm381194,663,845 - 94,677,518 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371194,525,161 - 94,538,807 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,479,941 - 94,486,630 (-)NCBImm8
Celera11104,282,927 - 104,296,600 (-)NCBICelera
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Xylt2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731565
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.