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Gene: Ppm1a (protein phosphatase 1A, magnesium dependent, alpha isoform) Mus musculus
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Symbol: Ppm1a
Name: protein phosphatase 1A, magnesium dependent, alpha isoform
Description: Exhibits phosphoprotein phosphatase activity. Involved in several processes, including cellular protein modification process; negative regulation of BMP signaling pathway; and positive regulation of protein export from nucleus. Localizes to the cytosol; membrane; and nucleus. Is expressed in several structures, including Peyer's patch; brain; ganglia; male reproductive gland or organ; and white fat. Orthologous to human PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310003C21Rik; 2900017D14Rik; AI427932; AU017636; MMPa-2; Mpp alpha; MPPa-1; PP2C-alpha; protein phosphatase 1A; protein phosphatase 2C isoform alpha; protein phosphatase IA
Orthologs:
Homo sapiens (human) : PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppm1a (protein phosphatase, Mg2+/Mn2+ dependent, 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1a (protein phosphatase, Mg2+/Mn2+ dependent 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A)
Canis lupus familiaris (dog) : PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1a (protein phosphatase, Mg2+/Mn2+ dependent 1A)
Sus scrofa (pig) : PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A)
Chlorocebus sabaeus (African green monkey) : PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A)
more info ...
Related Pseudogenes: Gm6004   Gm7211  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1272,757,455 - 72,799,819 (+)EnsemblGRCm38mm10GRCm38
GRCm381272,761,211 - 72,799,819 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371273,862,198 - 73,895,927 (+)NCBIGRCm37mm9NCBIm37
MGSCv361273,680,442 - 73,713,400 (+)NCBImm8
Celera1273,877,430 - 73,911,618 (+)NCBICelera
Cytogenetic Map12 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Ppm1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731573
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.