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Gene: SUCLG1 (succinate-CoA ligase alpha subunit) Homo sapiens
Symbol: SUCLG1
Name: succinate-CoA ligase alpha subunit
Description: Exhibits RNA binding activity. Predicted to be involved in nucleoside phosphate metabolic process; succinate metabolic process; and tricarboxylic acid cycle. Localizes to the cytosol; mitochondrion; and plasma membrane. Implicated in mitochondrial DNA depletion syndrome 9.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ21114; FLJ43513; G-ALPHA; GALPHA; MTDPS9; SCS-alpha; succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase, alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; succinyl-CoA synthetase subunit alpha; SUCLA1
Mus musculus (house mouse) : Suclg1 (succinate-CoA ligase, GDP-forming, alpha subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Suclg1 (succinate-CoA ligase, alpha subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Suclg1 (succinate-CoA ligase alpha subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SUCLG1 (succinate-CoA ligase alpha subunit)
Canis lupus familiaris (dog) : SUCLG1 (succinate-CoA ligase alpha subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Suclg1 (succinate-CoA ligase alpha subunit)
Sus scrofa (pig) : SUCLG1 (succinate-CoA ligase alpha subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38284,423,528 - 84,459,280 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37284,650,647 - 84,686,586 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36284,504,163 - 84,540,097 (-)NCBINCBI36hg18NCBI36
Build 34284,562,333 - 84,598,043NCBI
Celera284,479,456 - 84,515,401 (-)NCBI
Cytogenetic Map2p11.2NCBI
HuRef284,546,643 - 84,582,492 (-)NCBIHuRef
CHM1_1284,580,608 - 84,616,546 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SUCLG1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731609
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.