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Gene: POLA2 (DNA polymerase alpha 2, accessory subunit) Homo sapiens
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Symbol: POLA2
Name: DNA polymerase alpha 2, accessory subunit
Description: Predicted to have protein heterodimerization activity. Predicted to be involved in DNA replication initiation. Localizes to the alpha DNA polymerase:primase complex; cytosol; and nucleoplasm; PARTICIPATES IN DNA replication pathway; purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH (-)-demecolcine; (-)-epigallocatechin 3-gallate; 2-hydroxypropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA polymerase alpha 70 kDa subunit; DNA polymerase alpha subunit B; dna polymerase alpha subunit ii; FLJ21662; FLJ37250; polymerase (DNA directed), alpha 2 (70kD subunit); polymerase (DNA directed), alpha 2, accessory subunit; polymerase (DNA) alpha 2, accessory subunit; polymerase (DNA-directed), alpha (70kD)
Orthologs:
Mus musculus (house mouse) : Pola2 (polymerase (DNA directed), alpha 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pola2 (DNA polymerase alpha 2, accessory subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pola2 (DNA polymerase alpha 2, accessory subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : POLA2 (DNA polymerase alpha 2, accessory subunit)
Canis lupus familiaris (dog) : POLA2 (DNA polymerase alpha 2, accessory subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pola2 (DNA polymerase alpha 2, accessory subunit)
Sus scrofa (pig) : POLA2 (DNA polymerase alpha 2, accessory subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,261,917 - 65,306,269 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371165,029,432 - 65,065,088 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,786,006 - 64,821,664 (+)NCBINCBI36hg18NCBI36
Build 341164,786,007 - 64,821,663NCBI
Celera1162,355,790 - 62,391,446 (+)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1161,356,467 - 61,392,125 (+)NCBIHuRef
CHM1_11164,913,336 - 64,950,169 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on POLA2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731623
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.