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Gene: NPR3 (natriuretic peptide receptor 3) Homo sapiens
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Symbol: NPR3
Name: natriuretic peptide receptor 3
Description: Exhibits several functions, including chloride ion binding activity; natriuretic peptide receptor activity; and protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of cold-induced thermogenesis; osteoclast proliferation; and positive regulation of nitric-oxide synthase activity. Localizes to the protein-containing complex. Implicated in hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ANP-C; ANPR-C; ANPRC; atrial natriuretic peptide clearance receptor; atrial natriuretic peptide receptor 3; atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; atrionatriuretic peptide receptor type C; C5orf23; chromosome 5 open reading frame 23; FLJ14054; guanylate cyclase C; GUCY2B; hypothetical protein LOC79614; MGC22189; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); NPR-C; NPRC
Orthologs:
Mus musculus (house mouse) : Npr3 (natriuretic peptide receptor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Npr3 (natriuretic peptide receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npr3 (natriuretic peptide receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NPR3 (natriuretic peptide receptor 3)
Canis lupus familiaris (dog) : NPR3 (natriuretic peptide receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npr3 (natriuretic peptide receptor 3)
Sus scrofa (pig) : NPR3 (natriuretic peptide receptor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38532,689,076 - 32,791,724 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37532,710,284 - 32,791,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36532,747,422 - 32,823,013 (+)NCBINCBI36hg18NCBI36
Build 34532,747,421 - 32,823,009NCBI
Celera532,593,318 - 32,668,888 (+)NCBI
Cytogenetic Map5p13.3NCBI
HuRef532,678,571 - 32,759,879 (+)NCBIHuRef
CHM1_1532,712,833 - 32,793,931 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NPR3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731641
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.