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Gene: POU6F1 (POU class 6 homeobox 1) Homo sapiens
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Symbol: POU6F1
Name: POU class 6 homeobox 1
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to the actin cytoskeleton and nuclear body; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; antirheumatic drug; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain-5; brain-specific homeobox/POU domain protein 5; brn-5; BRN5; MPOU; mPOU homeobox protein; POU domain, class 6, transcription factor 1; TCFB1
Orthologs:
Mus musculus (house mouse) : Pou6f1 (POU domain, class 6, transcription factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pou6f1 (POU class 6 homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou6f1 (POU class 6 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POU6F1 (POU class 6 homeobox 1)
Canis lupus familiaris (dog) : POU6F1 (POU class 6 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou6f1 (POU class 6 homeobox 1)
Sus scrofa (pig) : POU6F1 (POU class 6 homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381251,186,936 - 51,219,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371251,580,719 - 51,611,477 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361249,869,232 - 49,897,744 (-)NCBINCBI36hg18NCBI36
Build 341249,869,231 - 49,897,744NCBI
Celera1250,382,323 - 50,412,965 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1248,613,565 - 48,644,376 (-)NCBIHuRef
CHM1_11251,546,938 - 51,577,697 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on POU6F1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731653
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.