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Gene: TMED10 (transmembrane p24 trafficking protein 10) Homo sapiens
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Symbol: TMED10
Name: transmembrane p24 trafficking protein 10
Description: Exhibits syntaxin binding activity. Involved in COPI-coated vesicle budding; intracellular protein transport; and regulation of amyloid-beta formation. Localizes to several cellular components, including the Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment; and gamma-secretase complex. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; Tmp-21-I; TMP21; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane protein Tmp21
Orthologs:
Mus musculus (house mouse) : Tmed10 (transmembrane p24 trafficking protein 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmed10 (transmembrane p24 trafficking protein 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmed10 (transmembrane p24 trafficking protein 10)
Pan paniscus (bonobo/pygmy chimpanzee) : TMED10 (transmembrane p24 trafficking protein 10)
Canis lupus familiaris (dog) : TMED10 (transmembrane p24 trafficking protein 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmed10 (transmembrane p24 trafficking protein 10)
Sus scrofa (pig) : TMED10 (transmembrane p24 trafficking protein 10)
more info ...
Related Pseudogenes: TMED10P1   TMED10P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381475,131,469 - 75,176,612 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371475,598,171 - 75,643,349 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361474,667,924 - 74,713,102 (-)NCBINCBI36hg18NCBI36
Build 341474,667,925 - 74,713,045NCBI
Celera1455,635,795 - 55,680,950 (-)NCBI
Cytogenetic Map14q24.3NCBI
HuRef1455,766,322 - 55,811,787 (-)NCBIHuRef
CHM1_11475,535,938 - 75,581,127 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TMED10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731656
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.