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Gene: TMED10 (transmembrane p24 trafficking protein 10) Homo sapiens
Symbol: TMED10
Name: transmembrane p24 trafficking protein 10
Description: Exhibits syntaxin binding activity. Involved in COPI-coated vesicle budding; intracellular protein transport; and regulation of amyloid-beta formation. Localizes to several cellular components, including the Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment; and gamma-secretase complex. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; Tmp-21-I; TMP21; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane protein Tmp21
Mus musculus (house mouse) : Tmed10 (transmembrane p24 trafficking protein 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmed10 (transmembrane p24 trafficking protein 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmed10 (transmembrane p24 trafficking protein 10)
Pan paniscus (bonobo/pygmy chimpanzee) : TMED10 (transmembrane p24 trafficking protein 10)
Canis lupus familiaris (dog) : TMED10 (transmembrane p24 trafficking protein 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmed10 (transmembrane p24 trafficking protein 10)
Sus scrofa (pig) : TMED10 (transmembrane p24 trafficking protein 10)
more info ...
Related Pseudogenes: TMED10P1   TMED10P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381475,131,469 - 75,176,612 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371475,598,171 - 75,643,349 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361474,667,924 - 74,713,102 (-)NCBINCBI36hg18NCBI36
Build 341474,667,925 - 74,713,045NCBI
Celera1455,635,795 - 55,680,950 (-)NCBI
Cytogenetic Map14q24.3NCBI
HuRef1455,766,322 - 55,811,787 (-)NCBIHuRef
CHM1_11475,535,938 - 75,581,127 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TMED10
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731656
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.