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Gene: MFN1 (mitofusin 1) Homo sapiens
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Symbol: MFN1
Name: mitofusin 1
Description: Exhibits GTPase activity and identical protein binding activity. Involved in several processes, including GTP metabolic process; mitochondrial fusion; and mitochondrial membrane fusion. Localizes to the integral component of mitochondrial outer membrane and outer mitochondrial membrane protein complex. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp762F247; FLJ20693; fzo homolog; hfzo1; hfzo2; MGC41806; mitochondrial transmembrane GTPase Fzo-1; mitochondrial transmembrane GTPase FZO-2; mitofusin-1; putative transmembrane GTPase; transmembrane GTPase MFN1
Orthologs:
Mus musculus (house mouse) : Mfn1 (mitofusin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mfn1 (mitofusin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mfn1 (mitofusin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MFN1 (mitofusin 1)
Canis lupus familiaris (dog) : MFN1 (mitofusin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mfn1 (mitofusin 1)
Sus scrofa (pig) : MFN1 (mitofusin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383179,347,709 - 179,394,936 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373179,065,480 - 179,111,014 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363180,548,174 - 180,593,708 (+)NCBINCBI36hg18NCBI36
Build 343180,548,181 - 180,593,708NCBI
Celera3177,496,491 - 177,542,028 (+)NCBI
Cytogenetic Map3q26.33NCBI
HuRef3176,468,758 - 176,514,186 (+)NCBIHuRef
CHM1_13179,028,464 - 179,074,130 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MFN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731663
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.