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Gene: Cx3cl1 (chemokine (C-X3-C motif) ligand 1) Mus musculus
Symbol: Cx3cl1
Name: chemokine (C-X3-C motif) ligand 1
Description: Exhibits chemokine activity. Involved in several processes, including angiogenesis involved in wound healing; leukocyte chemotaxis; and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Localizes to several cellular components, including cell surface; neuron projection; and neuronal cell body. Human ortholog(s) of this gene implicated in Cor pulmonale and common cold. Is expressed in several structures, including brain; genitourinary system; gut; nose; and respiratory system. Orthologous to human CX3CL1 (C-X3-C motif chemokine ligand 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AB030188; ABCD-3; AI848747; C-X3-C motif chemokine 1; CX3C; CX3C membrane-anchored chemokine; Cxc3; D8Bwg0439e; fractalkine; neurotactin; Scyd1; small inducible cytokine subfamily D, 1; small-inducible cytokine D1
Homo sapiens (human) : CX3CL1 (C-X3-C motif chemokine ligand 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cx3cl1 (C-X3-C motif chemokine ligand 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cx3cl1 (C-X3-C motif chemokine ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Canis lupus familiaris (dog) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cx3cl1 (C-X3-C motif chemokine ligand 1)
Sus scrofa (pig) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Chlorocebus sabaeus (African green monkey) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Heterocephalus glaber (naked mole-rat) : Cx3cl1 (C-X3-C motif chemokine ligand 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl894,772,009 - 94,782,427 (+)EnsemblGRCm38mm10GRCm38
GRCm38894,772,180 - 94,782,427 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37897,296,080 - 97,306,327 (+)NCBIGRCm37mm9NCBIm37
MGSCv36897,661,355 - 97,671,556 (+)NCBImm8
Celera899,100,414 - 99,110,655 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cx3cl1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731691
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.