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Gene: Cx3cl1 (chemokine (C-X3-C motif) ligand 1) Mus musculus
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Symbol: Cx3cl1
Name: chemokine (C-X3-C motif) ligand 1
Description: Exhibits chemokine activity. Involved in several processes, including angiogenesis involved in wound healing; leukocyte chemotaxis; and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Localizes to several cellular components, including cell surface; neuron projection; and neuronal cell body. Human ortholog(s) of this gene implicated in Cor pulmonale and common cold. Is expressed in several structures, including brain; genitourinary system; gut; nose; and respiratory system. Orthologous to human CX3CL1 (C-X3-C motif chemokine ligand 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AB030188; ABCD-3; AI848747; C-X3-C motif chemokine 1; CX3C; CX3C membrane-anchored chemokine; Cxc3; D8Bwg0439e; fractalkine; neurotactin; Scyd1; small inducible cytokine subfamily D, 1; small-inducible cytokine D1
Orthologs:
Homo sapiens (human) : CX3CL1 (C-X3-C motif chemokine ligand 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cx3cl1 (C-X3-C motif chemokine ligand 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cx3cl1 (C-X3-C motif chemokine ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Canis lupus familiaris (dog) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cx3cl1 (C-X3-C motif chemokine ligand 1)
Sus scrofa (pig) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Chlorocebus sabaeus (African green monkey) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Heterocephalus glaber (naked mole-rat) : Cx3cl1 (C-X3-C motif chemokine ligand 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl894,772,009 - 94,782,427 (+)EnsemblGRCm38mm10GRCm38
GRCm38894,772,180 - 94,782,427 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37897,296,080 - 97,306,327 (+)NCBIGRCm37mm9NCBIm37
MGSCv36897,661,355 - 97,671,556 (+)NCBImm8
Celera899,100,414 - 99,110,655 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cx3cl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731691
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.