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Gene: Cd81 (CD81 antigen) Mus musculus
Symbol: Cd81
Name: CD81 antigen
Description: Predicted to have cholesterol binding activity; signaling receptor binding activity; and virus receptor activity. Involved in several processes, including cellular response to low-density lipoprotein particle stimulus; positive regulation of immune response; and syncytium formation by plasma membrane fusion. Localizes to the membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; nervous system; and sensory organ. Orthologous to human CD81 (CD81 molecule); PARTICIPATES IN B cell receptor signaling pathway; hepatitis C pathway; malaria pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 26 kDa cell surface protein TAPA-1; Tapa-1; Tapa1; target of the antiproliferative antibody 1; Tspan28
Homo sapiens (human) : CD81 (CD81 molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd81 (Cd81 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd81 (CD81 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD81 (CD81 molecule)
Canis lupus familiaris (dog) : CD81 (CD81 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd81 (CD81 molecule)
Sus scrofa (pig) : CD81 (CD81 molecule)
Chlorocebus sabaeus (green monkey) : CD81 (CD81 molecule)
Heterocephalus glaber (naked mole-rat) : Cd81 (CD81 molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7143,052,739 - 143,067,934 (+)Ensembl
GRCm387143,052,750 - 143,067,930 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377150,238,655 - 150,253,835 (+)NCBIGRCm37mm9NCBIm37
MGSCv367142,862,185 - 142,877,314 (+)NCBImm8
Celera7142,808,354 - 142,823,535 (+)NCBICelera
Cytogenetic Map7 F5NCBI
cM Map788.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cd81
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731701
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.