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Gene: GDI1 (GDP dissociation inhibitor 1) Homo sapiens
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Symbol: GDI1
Name: GDP dissociation inhibitor 1
Description: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific cognitive disability. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1A; FLJ41411; GDI-1; GDIL; guanosine diphosphate dissociation inhibitor 1; mental retardation, X-linked 41; mental retardation, X-linked 48; MRX41; MRX48; oligophrenin-2; OPHN2; rab GDI alpha; rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor, alpha; RABGD1A; RABGDIA; testis secretory sperm-binding protein Li 208a; XAP-4
Orthologs:
Mus musculus (house mouse) : Gdi1 (guanosine diphosphate (GDP) dissociation inhibitor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gdi1 (GDP dissociation inhibitor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdi1 (GDP dissociation inhibitor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GDI1 (GDP dissociation inhibitor 1)
Canis lupus familiaris (dog) : GDI1 (GDP dissociation inhibitor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdi1 (GDP dissociation inhibitor 1)
Sus scrofa (pig) : GDI1 (GDP dissociation inhibitor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,436,913 - 154,443,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,665,259 - 153,671,814 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,318,715 - 153,325,008 (+)NCBINCBI36hg18NCBI36
Build 34X153,234,158 - 153,235,516NCBI
CeleraX153,826,304 - 153,832,858 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,217,606 - 142,249,463 (+)NCBIHuRef
CHM1_1X153,576,897 - 153,583,451 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Sequence

Nucleotide Sequences
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Additional Information

External Database Links
 
More on GDI1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731728
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.