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Gene: TNMD (tenomodulin) Homo sapiens
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Symbol: TNMD
Name: tenomodulin
Description: This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BRICD4; BRICHOS domain containing 4; CHM1-LIKE; CHM1L; chondromodulin I-like; chondromodulin-1-like protein; chondromodulin-I-like protein; chondromodulin-IB; hChM1L; hTeM; myodulin; TEM; tendin
Orthologs:
Mus musculus (house mouse) : Tnmd (tenomodulin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tnmd (tenomodulin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnmd (tenomodulin)
Pan paniscus (bonobo/pygmy chimpanzee) : TNMD (tenomodulin)
Canis lupus familiaris (dog) : TNMD (tenomodulin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnmd (tenomodulin)
Sus scrofa (pig) : TNMD (tenomodulin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X100,584,793 - 100,599,885 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X99,839,790 - 99,855,007 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X99,726,446 - 99,741,538 (+)NCBINCBI36hg18NCBI36
Build 34X99,645,974 - 99,661,022NCBI
CeleraX100,358,526 - 100,373,618 (+)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX89,639,690 - 89,654,782 (+)NCBIHuRef
CHM1_1X99,732,699 - 99,747,791 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TNMD
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731806
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.