Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ACVR2A (activin A receptor type 2A) Homo sapiens
Analyze
Symbol: ACVR2A
Name: activin A receptor type 2A
Description: Exhibits coreceptor activity and protein serine/threonine kinase activity. Contributes to activin binding activity and activin-activated receptor activity. Involved in several processes, including positive regulation of ossification; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and transmembrane receptor protein serine/threonine kinase signaling pathway. Localizes to the cytoplasm; inhibin-betaglycan-ActRII complex; and receptor complex. Implicated in colon cancer. Biomarker of pancreatic cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activin A receptor type IIA; activin A receptor, type IIA; activin receptor iia; activin receptor type-2A; ACTRII; ACVR2
Orthologs:
Mus musculus (house mouse) : Acvr2a (activin receptor IIA)  MGI  Alliance
Rattus norvegicus (Norway rat) : Acvr2a (activin A receptor type 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr2a (activin A receptor type 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR2A (activin A receptor type 2A)
Canis lupus familiaris (dog) : ACVR2A (activin A receptor type 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr2a (activin A receptor type 2A)
Sus scrofa (pig) : ACVR2A (activin A receptor type 2A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382147,844,517 - 147,930,827 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372148,602,086 - 148,688,396 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362148,319,040 - 148,404,863 (+)NCBINCBI36hg18NCBI36
Build 342148,436,303 - 148,519,242NCBI
Celera2142,316,710 - 142,402,536 (+)NCBI
Cytogenetic Map2q22.3-q23.1NCBI
HuRef2140,599,673 - 140,685,765 (+)NCBIHuRef
CHM1_12148,607,725 - 148,694,041 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ACVR2A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731811
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.