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Gene: CDH2 (cadherin 2) Homo sapiens
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Symbol: CDH2
Name: cadherin 2
Description: Exhibits alpha-catenin binding activity; beta-catenin binding activity; and gamma-catenin binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and nervous system development. Localizes to several cellular components, including adherens junction; catenin complex; and lamellipodium. Colocalizes with cortical actin cytoskeleton. Implicated in arrhythmogenic right ventricular cardiomyopathy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cadherin 2, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal); cadherin-2; calcium-dependent adhesion protein, neuronal; CD325; CDHN; CDw325; N-cadherin 1; NCAD; neural cadherin; neural-cadherin
Orthologs:
Mus musculus (house mouse) : Cdh2 (cadherin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdh2 (cadherin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh2 (cadherin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH2 (cadherin 2)
Canis lupus familiaris (dog) : CDH2 (cadherin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh2 (cadherin 2)
Sus scrofa (pig) : CDH2 (cadherin 2)
Chlorocebus sabaeus (African green monkey) : CDH2 (cadherin 2)
Heterocephalus glaber (naked mole-rat) : Cdh2 (cadherin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1827,950,966 - 28,177,130 (-)EnsemblGRCh38hg38GRCh38
GRCh381827,932,878 - 28,177,130 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371825,530,930 - 25,757,445 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361823,784,933 - 24,011,189 (-)NCBINCBI36hg18NCBI36
Build 341823,784,933 - 24,011,189NCBI
Celera1822,342,317 - 22,568,868 (-)NCBI
Cytogenetic Map18q12.1NCBI
HuRef1822,383,072 - 22,579,896 (-)NCBIHuRef
CHM1_11825,458,395 - 25,684,846 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

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