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Gene: VEGFD (vascular endothelial growth factor D) Homo sapiens
Symbol: VEGFD
Name: vascular endothelial growth factor D
Description: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-fos induced growth factor; c-fos induced growth factor (vascular endothelial growth factor D); c-fos-induced growth factor; FIGF; VEGF-D
Mus musculus (house mouse) : Vegfd (vascular endothelial growth factor D)  MGI  Alliance
Rattus norvegicus (Norway rat) : Vegfd (vascular endothelial growth factor D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vegfd (vascular endothelial growth factor D)
Pan paniscus (bonobo/pygmy chimpanzee) : VEGFD (vascular endothelial growth factor D)
Canis lupus familiaris (dog) : VEGFD (vascular endothelial growth factor D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vegfd (vascular endothelial growth factor D)
Sus scrofa (pig) : VEGFD (vascular endothelial growth factor D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X15,345,591 - 15,384,413 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,363,713 - 15,402,535 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,273,639 - 15,312,498 (-)NCBINCBI36hg18NCBI36
Build 34X15,123,375 - 15,162,234NCBI
CeleraX19,479,224 - 19,518,092 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,122,815 - 13,159,253 (-)NCBIHuRef
CHM1_1X15,394,667 - 15,433,457 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on VEGFD
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731830
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.