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Gene: VEGFD (vascular endothelial growth factor D) Homo sapiens
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Symbol: VEGFD
Name: vascular endothelial growth factor D
Description: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-fos induced growth factor; c-fos induced growth factor (vascular endothelial growth factor D); c-fos-induced growth factor; FIGF; VEGF-D
Orthologs:
Mus musculus (house mouse) : Vegfd (vascular endothelial growth factor D)  MGI  Alliance
Rattus norvegicus (Norway rat) : Vegfd (vascular endothelial growth factor D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vegfd (vascular endothelial growth factor D)
Pan paniscus (bonobo/pygmy chimpanzee) : VEGFD (vascular endothelial growth factor D)
Canis lupus familiaris (dog) : VEGFD (vascular endothelial growth factor D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vegfd (vascular endothelial growth factor D)
Sus scrofa (pig) : VEGFD (vascular endothelial growth factor D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X15,345,591 - 15,384,413 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,363,713 - 15,402,535 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,273,639 - 15,312,498 (-)NCBINCBI36hg18NCBI36
Build 34X15,123,375 - 15,162,234NCBI
CeleraX19,479,224 - 19,518,092 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,122,815 - 13,159,253 (-)NCBIHuRef
CHM1_1X15,394,667 - 15,433,457 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on VEGFD
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731830
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.