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Gene: DRD5 (dopamine receptor D5) Homo sapiens
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Symbol: DRD5
Name: dopamine receptor D5
Description: Exhibits dopamine binding activity and dopamine neurotransmitter receptor activity. Involved in adenylate cyclase-activating dopamine receptor signaling pathway; negative regulation of NAD(P)H oxidase activity; and reactive oxygen species metabolic process. Localizes to ciliary membrane and non-motile cilium. Implicated in attention deficit hyperactivity disorder and blepharospasm. Biomarker of Alzheimer's disease and Parkinson's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D(1B) dopamine receptor; d(5) dopamine receptor; D1B; D1beta dopamine receptor; DBDR; dopamine D5 receptor; dopamine receptor 5; dopamine receptor D1B; DRD1B; DRD1L2; MGC10601
Orthologs:
Mus musculus (house mouse) : Drd5 (dopamine receptor D5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Drd5 (dopamine receptor D5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Drd5 (dopamine receptor D5)
Pan paniscus (bonobo/pygmy chimpanzee) : DRD5 (dopamine receptor D5)
Canis lupus familiaris (dog) : DRD5 (dopamine receptor D5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Drd5 (dopamine receptor D5)
Sus scrofa (pig) : DRD5 (dopamine receptor D5)
Chlorocebus sabaeus (African green monkey) : DRD5 (dopamine receptor D5)
Heterocephalus glaber (naked mole-rat) : Drd5 (dopamine receptor D5)
more info ...
Related Pseudogenes: DRD5P1   DRD5P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl49,781,634 - 9,784,009 (+)EnsemblGRCh38hg38GRCh38
GRCh3849,781,634 - 9,784,009 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3749,783,258 - 9,785,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3649,392,701 - 9,394,731 (+)NCBINCBI36hg18NCBI36
Build 3449,459,871 - 9,461,901NCBI
Celera410,266,117 - 10,268,492 (+)NCBI
Cytogenetic Map4p16.1NCBI
HuRef49,117,663 - 9,120,038 (+)NCBIHuRef
CHM1_149,781,174 - 9,783,549 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
 
More on DRD5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731837
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.