Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1) Homo sapiens
Symbol: RBCK1
Name: RANBP2-type and C3HC4-type zinc finger containing 1
Description: Exhibits identical protein binding activity; ubiquitin binding activity; and ubiquitin-protein transferase activity. Involved in several processes, including T cell receptor signaling pathway; cellular protein metabolic process; and regulation of DNA-binding transcription factor activity. Localizes to the LUBAC complex. Implicated in glycogen storage disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C20orf18; HBV associated factor 4; HBV-associated factor 4; heme-oxidized IRP2 ubiquitin ligase 1; hepatitis B virus X-associated protein 4; HOIL-1; HOIL1; PBMEI; PGBM1; protein kinase c-binding protein beta15; RanBP-type and C3HC4-type zinc finger containing 1; ranBP-type and C3HC4-type zinc finger-containing protein 1; RBCC protein interacting with PKC1; RBCK2; RING finger protein 54; RING-type E3 ubiquitin transferase HOIL-1; RNF54; UBCE7IP3; ubiquitin conjugating enzyme 7 interacting protein 3; ubiquitin-conjugating enzyme 7-interacting protein 3; XAP3; XAP4; ZRANB4
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3820408,050 - 432,139 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3720388,696 - 411,610 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3620336,709 - 359,610 (+)NCBINCBI36hg18NCBI36
Build 3420336,755 - 359,610NCBI
Celera20483,557 - 506,462 (+)NCBI
Cytogenetic Map20p13NCBI
HuRef20340,142 - 362,963 (+)NCBIHuRef
CHM1_120388,695 - 412,785 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RBCK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731853
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.