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Gene: AZIN1 (antizyme inhibitor 1) Homo sapiens
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Symbol: AZIN1
Name: antizyme inhibitor 1
Description: Exhibits ornithine decarboxylase activator activity. Involved in negative regulation of protein catabolic process and positive regulation of polyamine transmembrane transport. Predicted to localize to the cytoplasm and nucleus. Implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AZI; AZI1; AZIA1; MGC3832; MGC691; OAZI; OAZIN; ODC1L; ornithine decarboxylase 1-like; ornithine decarboxylase antizyme inhibitor
Orthologs:
Mus musculus (house mouse) : Azin1 (antizyme inhibitor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Azin1 (antizyme inhibitor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Azin1 (antizyme inhibitor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AZIN1 (antizyme inhibitor 1)
Canis lupus familiaris (dog) : AZIN1 (antizyme inhibitor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Azin1 (antizyme inhibitor 1)
Sus scrofa (pig) : AZIN1 (antizyme inhibitor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388102,826,302 - 102,864,200 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378103,838,536 - 103,876,905 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368103,907,712 - 103,945,573 (-)NCBINCBI36hg18NCBI36
Build 348103,909,226 - 103,945,551NCBI
Celera8100,025,705 - 100,063,568 (-)NCBI
Cytogenetic Map8q22.3NCBI
HuRef899,039,532 - 99,077,262 (-)NCBIHuRef
CHM1_18103,878,797 - 103,916,687 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on AZIN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731863
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.