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Gene: NUDT1 (nudix hydrolase 1) Homo sapiens
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Symbol: NUDT1
Name: nudix hydrolase 1
Description: Exhibits GTPase activity and nucleoside-triphosphate diphosphatase activity. Involved in DNA protection; dATP catabolic process; and dGTP catabolic process. Localizes to the cytosol; mitochondrial matrix; and nucleus. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2-hydroxy-dATP diphosphatase; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-dGTPase; MTH1; mutt (e. coli) human homolog (8-oxo-dgtpase); mutT human homolog 1; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; nudix motif 1
Orthologs:
Mus musculus (house mouse) : Nudt1 (nudix (nucleoside diphosphate linked moiety X)-type motif 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nudt1 (nudix hydrolase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nudt1 (nudix hydrolase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NUDT1 (nudix hydrolase 1)
Canis lupus familiaris (dog) : NUDT1 (nudix hydrolase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nudt1 (nudix hydrolase 1)
Sus scrofa (pig) : NUDT1 (nudix hydrolase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3872,242,222 - 2,251,145 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3772,281,857 - 2,290,780 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3672,248,383 - 2,257,306 (+)NCBINCBI36hg18NCBI36
Build 3472,055,780 - 2,064,021NCBI
Celera72,251,549 - 2,260,471 (+)NCBI
Cytogenetic Map7p22.3NCBI
HuRef72,201,140 - 2,210,062 (+)NCBIHuRef
CHM1_172,281,464 - 2,290,386 (+)NCBICHM1_1
CRA_TCAGchr7v272,330,533 - 2,339,455 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NUDT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731881
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.