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Gene: Cdk1 (cyclin-dependent kinase 1) Mus musculus
Symbol: Cdk1
Name: cyclin-dependent kinase 1
Description: Exhibits Hsp70 protein binding activity; chromatin binding activity; and cyclin-dependent protein serine/threonine kinase activity. Involved in several processes, including mitotic G2 DNA damage checkpoint; mitotic cell cycle phase transition; and protein phosphorylation. Colocalizes with mitochondrial matrix. Human ortholog(s) of this gene implicated in breast cancer; cervical cancer; and urinary bladder cancer. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human CDK1 (cyclin dependent kinase 1); PARTICIPATES IN cell cycle pathway, mitotic; p53 signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cdc2; Cdc2a; cell cycle p34 CDC2 kinase protein; cell division control protein 2 homolog; cell division cycle 2 homolog A; cell division cycle control protein 2a; cell division protein kinase 1; p34 protein kinase; p34
Homo sapiens (human) : CDK1 (cyclin dependent kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdk1 (cyclin-dependent kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk1 (cyclin dependent kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK1 (cyclin dependent kinase 1)
Canis lupus familiaris (dog) : CDK1 (cyclin dependent kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk1 (cyclin dependent kinase 1)
Sus scrofa (pig) : CDK1 (cyclin dependent kinase 1)
Chlorocebus sabaeus (African green monkey) : CDK1 (cyclin dependent kinase 1)
Heterocephalus glaber (naked mole-rat) : Cdk1 (cyclin dependent kinase 1)
more info ...
Related Pseudogenes: Gm18371   Gm49852  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1069,335,146 - 69,352,938 (-)EnsemblGRCm38mm10GRCm38
GRCm381069,335,146 - 69,352,912 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371068,799,383 - 68,815,660 (-)NCBIGRCm37mm9NCBIm37
MGSCv361068,731,992 - 68,748,269 (-)NCBImm8
Celera1070,426,785 - 70,443,097 (-)NCBICelera
Cytogenetic Map10B5.3NCBI
cM Map1036.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cdk1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731890
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.