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Gene: Atp6v0c (ATPase, H+ transporting, lysosomal V0 subunit C) Mus musculus
Symbol: Atp6v0c
Name: ATPase, H+ transporting, lysosomal V0 subunit C
CRRD ID: 731893
Description: Predicted to have proton-exporting ATPase activity, phosphorylative mechanism; proton-transporting ATPase activity, rotational mechanism; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of autophagic cell death; positive regulation of ERK1 and ERK2 cascade; and positive regulation of Wnt signaling pathway. Predicted to localize to several cellular components, including Golgi apparatus; lysosome; and synaptic vesicle. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c); PARTICIPATES IN oxidative phosphorylation pathway; rheumatoid arthritis pathway; tuberculosis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A; At; Atp; Atp6; Atp6c; Atp6c2; Atp6l; ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa; ATPase, H+ transporting, lysosomal 16kD, V0 subunit C; ATPase, H+ transporting, lysosomal 2; Atpl; Atpl-rs1; H(+)-ATPase (mvp); PL; PL16; pro; V-ATPase 16 kDa proteolipid subunit; V-type proton ATPase 16 kDa proteolipid subunit; vacuolar proton pump 16 kDa proteolipid subunit; VATL; Vma3
Homo sapiens (human) : ATP6V0C (ATPase H+ transporting V0 subunit c)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atp6v0c (ATPase H+ transporting V0 subunit C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp6v0c (ATPase H+ transporting V0 subunit c)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP6V0C (ATPase H+ transporting V0 subunit c)
Canis lupus familiaris (dog) : ATP6V0C (ATPase H+ transporting V0 subunit c)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp6v0c (ATPase H+ transporting V0 subunit c)
Sus scrofa (pig) : ATP6V0C (ATPase H+ transporting V0 subunit c)
Chlorocebus sabaeus (African green monkey) : ATP6V0C (ATPase H+ transporting V0 subunit c)
Heterocephalus glaber (naked mole-rat) : Atp6v0c (ATPase H+ transporting V0 subunit c)
more info ...
Related Pseudogenes: Atp6v0c-ps1   Atp6v0c-ps2  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391724,382,839 - 24,388,652 (-)NCBI
GRCm381724,163,865 - 24,169,678 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,163,866 - 24,169,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,300,833 - 24,306,374 (-)NCBIGRCm37mm9NCBIm37
MGSCv361723,891,488 - 23,897,029 (-)NCBImm8
Celera1724,669,200 - 24,674,661 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atp6v0c
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731893
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.