Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: KCNE2 (potassium voltage-gated channel subfamily E regulatory subunit 2) Homo sapiens
Analyze
Symbol: KCNE2
Name: potassium voltage-gated channel subfamily E regulatory subunit 2
Description: Exhibits ion channel binding activity; potassium channel regulator activity; and voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Contributes to delayed rectifier potassium channel activity and inward rectifier potassium channel activity. Involved in several processes, including potassium ion transmembrane transport; regulation of heart rate by cardiac conduction; and regulation of ion transmembrane transport. Localizes to the cell surface and voltage-gated potassium channel complex. Implicated in atrial fibrillation; familial atrial fibrillation; long QT syndrome; and long QT syndrome 6.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFB4; cardiac voltage-gated potassium channel accessory subunit 2; LQT5; LQT6; MGC138292; minimum potassium ion channel-related peptide 1; minK-related peptide 1; minK-related peptide-1; MIRP1; potassium channel subunit beta MiRP1; potassium channel subunit, MiRP1; potassium channel, voltage gated subfamily E regulatory beta subunit 2; potassium voltage-gated channel subfamily E member 2; potassium voltage-gated channel, Isk-related family, member 2; voltage-gated K+ channel subunit MIRP1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382134,364,024 - 34,371,141 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372135,736,323 - 35,743,440 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362134,658,193 - 34,665,310 (+)NCBINCBI36hg18NCBI36
Build 342134,658,192 - 34,665,310NCBI
Celera2120,935,893 - 20,943,010 (+)NCBI
Cytogenetic Map21q22.11NCBI
HuRef2121,214,794 - 21,221,877 (+)NCBIHuRef
CHM1_12135,298,575 - 35,305,689 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KCNE2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731917
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.