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Gene: Dlg2 (discs large MAGUK scaffold protein 2) Mus musculus
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Symbol: Dlg2
Name: discs large MAGUK scaffold protein 2
Description: A structural constituent of postsynaptic density. Involved in several processes, including axo-dendritic protein transport; cellular response to potassium ion; and neurotransmitter receptor localization to postsynaptic specialization membrane. Localizes to several cellular components, including glutamatergic synapse; juxtaparanode region of axon; and postsynaptic density. Predicted to colocalize with ionotropic glutamate receptor complex and voltage-gated potassium channel complex. Is expressed in jaw bone; nervous system; and retina. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A330103J02Rik; B230218P12Rik; B330007M19Rik; channel-associated protein of synapse-110; chapsyn-110; discs large homolog 2; discs large MAGUK scaffold protein 2 eta; discs large MAGUK scaffold protein 2 gamma; discs, large homolog 2; discs, large homolog 2 (Drosophila); disks large homolog 2; Dlgh2; Gm1197; Gm21505; hypothetical protein LOC78880; postsynaptic density protein PSD-93; predicted gene, 21505; PSD93; RIKEN cDNA B230218P12 gene
Orthologs:
Homo sapiens (human) : DLG2 (discs large MAGUK scaffold protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dlg2 (discs large MAGUK scaffold protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlg2 (discs large MAGUK scaffold protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DLG2 (discs large MAGUK scaffold protein 2)
Canis lupus familiaris (dog) : DLG2 (discs large MAGUK scaffold protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlg2 (discs large MAGUK scaffold protein 2)
Sus scrofa (pig) : DLG2 (discs large MAGUK scaffold protein 2)
Chlorocebus sabaeus (African green monkey) : DLG2 (discs large MAGUK scaffold protein 2)
Heterocephalus glaber (naked mole-rat) : Dlg2 (discs large MAGUK scaffold protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl790,476,672 - 92,449,247 (+)EnsemblGRCm38mm10GRCm38
GRCm38790,476,188 - 92,449,246 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37798,239,296 - 99,597,599 (+)NCBIGRCm37mm9NCBIm37
MGSCv36790,966,199 - 92,319,809 (+)NCBImm8
Celera788,404,695 - 89,743,714 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map751.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Dlg2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731939
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.