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Gene: Ppard (peroxisome proliferator activator receptor delta) Mus musculus
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Symbol: Ppard
Name: peroxisome proliferator activator receptor delta
Description: Exhibits DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including animal organ development; keratinocyte migration; and regulation of gene expression. Localizes to nuclear chromatin. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and sensory organ. Used to study Huntington's disease and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta); PARTICIPATES IN acute myeloid leukemia pathway; Wnt signaling pathway; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; (S)-naringenin; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mPPAR(delta); Nr1c2; NUC-1; NUC1; nuclear hormone receptor 1; nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; peroxisome proliferator-activated receptor delta; PPAR-beta; PPAR-delta; PPAR[b]; Pparb; Pparb/d; PPARdelta; PPARdelta/beta
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1728,232,700 - 28,301,474 (+)EnsemblGRCm38mm10GRCm38
GRCm381728,232,754 - 28,301,469 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371728,369,699 - 28,438,414 (+)NCBIGRCm37mm9NCBIm37
MGSCv361727,960,392 - 28,029,058 (+)NCBImm8
Celera1728,786,405 - 28,855,326 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ppard
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731946
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.