Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CDC5L (cell division cycle 5 like) Homo sapiens
Analyze
Symbol: CDC5L
Name: cell division cycle 5 like
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and WD40-repeat domain binding activity. Involved in mRNA splicing, via spliceosome; positive regulation of transcription by RNA polymerase II; and signal transduction involved in DNA damage checkpoint. Localizes to the Prp19 complex; cytoplasm; and nucleus. Colocalizes with the DNA replication factor A complex. Implicated in osteosarcoma. Biomarker of esophagus adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC5; CDC5 (cell division cycle 5, S. pombe, homolog)-like; CDC5 cell division cycle 5-like; CDC5-LIKE; Cdc5-related protein; CEF1; Cell division cycle 5, S. pombe, homolog-like; cell division cycle 5-like (s. pombe); cell division cycle 5-like protein; dJ319D22.1; dJ319D22.1 (CDC5-like protein); hCDC5; KIAA0432; PCDC5RP; pombe cdc5-related protein
Orthologs:
Mus musculus (house mouse) : Cdc5l (cell division cycle 5-like (S. pombe))  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc5l (cell division cycle 5-like)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc5l (cell division cycle 5 like)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC5L (cell division cycle 5 like)
Canis lupus familiaris (dog) : CDC5L (cell division cycle 5 like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc5l (cell division cycle 5 like)
Sus scrofa (pig) : CDC5L (cell division cycle 5 like)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,387,706 - 44,450,425 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37644,355,251 - 44,418,161 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36644,463,280 - 44,522,758 (+)NCBINCBI36hg18NCBI36
Build 34644,463,279 - 44,522,757NCBI
Celera645,908,480 - 45,967,835 (+)NCBI
Cytogenetic Map6p21.1NCBI
HuRef644,077,869 - 44,140,670 (+)NCBIHuRef
CHM1_1644,358,890 - 44,421,686 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDC5L
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731949
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.