Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TCF12 (transcription factor 12) Homo sapiens
Analyze
Symbol: TCF12
Name: transcription factor 12
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and bHLH transcription factor binding activity. Contributes to transcription regulatory region DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to the cytoplasm and nucleus. Implicated in craniosynostosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHb20; class B basic helix-loop-helix protein 20; CRS3; DNA-binding protein HTF4; E-box-binding protein; HEB; helix-loop-helix transcription factor 4; HsT17266; HTF4; p64; TCF-12; transcription factor 12 (HTF4, helix-loop-helix transcription factors 4); transcription factor HTF-4
Orthologs:
Mus musculus (house mouse) : Tcf12 (transcription factor 12)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tcf12 (transcription factor 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tcf12 (transcription factor 12)
Pan paniscus (bonobo/pygmy chimpanzee) : TCF12 (transcription factor 12)
Canis lupus familiaris (dog) : TCF12 (transcription factor 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcf12 (transcription factor 12)
Sus scrofa (pig) : TCF12 (transcription factor 12)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381556,918,090 - 57,292,595 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371557,210,833 - 57,580,716 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361554,998,125 - 55,368,008 (+)NCBINCBI36hg18NCBI36
Build 341555,298,946 - 55,368,004NCBI
Celera1534,101,089 - 34,470,989 (+)NCBI
Cytogenetic Map15q21.3NCBI
HuRef1534,034,113 - 34,404,326 (+)NCBIHuRef
CHM1_11557,328,515 - 57,701,580 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TCF12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731955
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.