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Gene: Plpp3 (phospholipid phosphatase 3) Mus musculus
Symbol: Plpp3
Name: phospholipid phosphatase 3
Description: Exhibits integrin binding activity; lipid phosphatase activity; and sphingosine-1-phosphate phosphatase activity. Involved in several processes, including Bergmann glial cell differentiation; regulation of protein phosphorylation; and regulation of signal transduction. Localizes to the plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human PLPP3 (phospholipid phosphatase 3); PARTICIPATES IN glycerophospholipid metabolic pathway; sphingolipid metabolic pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110003O22Rik; 2610002D05Rik; AV025606; D4Bwg0538e; D4Bwg1535e; lipid phosphate phosphohydrolase 3; Lpp3; PAP-2b; PAP2-beta; PAP2b; phosphatidate phosphohydrolase type 2b; phosphatidic acid phosphatase 2b; phosphatidic acid phosphatase type 2B; Ppab2b; Ppap2b; PRG-2
Homo sapiens (human) : PLPP3 (phospholipid phosphatase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plpp3 (phospholipid phosphatase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plpp3 (phospholipid phosphatase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PLPP3 (phospholipid phosphatase 3)
Canis lupus familiaris (dog) : PLPP3 (phospholipid phosphatase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plpp3 (phospholipid phosphatase 3)
Sus scrofa (pig) : PLPP3 (phospholipid phosphatase 3)
Chlorocebus sabaeus (green monkey) : PLPP3 (phospholipid phosphatase 3)
Heterocephalus glaber (naked mole-rat) : Plpp3 (phospholipid phosphatase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4105,157,347 - 105,232,764 (+)Ensembl
GRCm384105,157,347 - 105,232,767 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374104,829,952 - 104,905,372 (+)NCBIGRCm37mm9NCBIm37
MGSCv364104,655,279 - 104,730,699 (+)NCBImm8
Celera4103,508,199 - 103,583,768 (+)NCBICelera
Cytogenetic Map4 C6NCBI
cM Map449.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Plpp3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731972
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.