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Gene: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1) Mus musculus
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Symbol: Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Description: Exhibits identical protein binding activity; large conductance calcium-activated potassium channel activity; and voltage-gated potassium channel activity. Involved in several processes, including adult walking behavior; eye blink reflex; and locomotor rhythm. Localizes to several cellular components, including apical plasma membrane; external side of plasma membrane; and voltage-gated potassium channel complex. Predicted to colocalize with mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in Alzheimer's disease and idiopathic generalized epilepsy. Orthologous to human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1); INTERACTS WITH 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730414M22Rik; BK channel alpha subunit; BKCa; BKCA alpha; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel, subfamily M subunit alpha-1; k(VCA)alpha; KCa1.1; maxi K channel; MaxiK; mSlo; mSlo1; RIKEN cDNA 5730414M22 gene; Slo; slo homolog; slo-alpha; Slo1; slowpoke homolog
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1423,289,431 - 24,014,491 (-)EnsemblGRCm38mm10GRCm38
GRCm381423,292,288 - 24,005,110 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371424,117,983 - 24,823,427 (-)NCBIGRCm37mm9NCBIm37
MGSCv361422,088,573 - 22,792,482 (-)NCBImm8
Celera1419,676,577 - 20,379,488 (-)NCBICelera
Cytogenetic Map14A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences