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Gene: GNB5 (G protein subunit beta 5) Homo sapiens
Symbol: GNB5
Name: G protein subunit beta 5
Description: Exhibits G-protein gamma-subunit binding activity; GTPase activator activity; and chaperone binding activity. Involved in dopamine receptor signaling pathway; negative regulation of voltage-gated calcium channel activity; and positive regulation of GTPase activity. Localizes to cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ37457; FLJ43714; G protein, beta subunit 5L; G protein, beta-5 subunit; GB5; gbeta5; guanine nucleotide binding protein (G protein), beta 5; guanine nucleotide binding protein beta 5; guanine nucleotide-binding protein subunit beta-5; guanine nucleotide-binding protein, beta subunit 5L; IDDCA; LADCI; transducin beta chain 5
Mus musculus (house mouse) : Gnb5 (guanine nucleotide binding protein (G protein), beta 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gnb5 (G protein subunit beta 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnb5 (G protein subunit beta 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GNB5 (G protein subunit beta 5)
Canis lupus familiaris (dog) : GNB5 (G protein subunit beta 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnb5 (G protein subunit beta 5)
Sus scrofa (pig) : GNB5 (G protein subunit beta 5)
Chlorocebus sabaeus (African green monkey) : GNB5 (G protein subunit beta 5)
Heterocephalus glaber (naked mole-rat) : Gnb5 (G protein subunit beta 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1552,115,105 - 52,191,369 (-)EnsemblGRCh38hg38GRCh38
GRCh381552,115,100 - 52,191,392 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371552,413,123 - 52,483,565 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361550,200,415 - 50,270,857 (-)NCBINCBI36hg18NCBI36
Build 341550,201,694 - 50,270,857NCBI
Celera1529,307,586 - 29,378,010 (-)NCBI
Cytogenetic Map15q21.2NCBI
HuRef1529,244,091 - 29,314,529 (-)NCBIHuRef
CHM1_11552,531,429 - 52,601,868 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GNB5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731985
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.