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Gene: Gnb5 (guanine nucleotide binding protein (G protein), beta 5) Mus musculus
Symbol: Gnb5
Name: guanine nucleotide binding protein (G protein), beta 5
Description: Predicted to have several functions, including G-protein gamma-subunit binding activity; GTPase activating protein binding activity; and GTPase activator activity. Involved in G protein-coupled receptor signaling pathway. Localizes to several cellular components, including the photoreceptor inner segment; photoreceptor outer segment; and presynapse. Is expressed in several structures, including brain; eye; genitourinary system; liver; and lung. Orthologous to human GNB5 (G protein subunit beta 5); PARTICIPATES IN eicosanoid signaling pathway; visual phototransduction pathway; glutamate signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; aldrin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: flail; flailer; flr; Gbeta5; GBS; guanine nucleotide binding protein, beta 5; guanine nucleotide-binding protein subunit beta-5; hug; transducin beta chain 5
Homo sapiens (human) : GNB5 (G protein subunit beta 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gnb5 (G protein subunit beta 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnb5 (G protein subunit beta 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GNB5 (G protein subunit beta 5)
Canis lupus familiaris (dog) : GNB5 (G protein subunit beta 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnb5 (G protein subunit beta 5)
Sus scrofa (pig) : GNB5 (G protein subunit beta 5)
Chlorocebus sabaeus (green monkey) : GNB5 (G protein subunit beta 5)
Heterocephalus glaber (naked mole-rat) : Gnb5 (G protein subunit beta 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl975,306,288 - 75,345,876 (+)Ensembl
GRCm38975,306,288 - 75,345,923 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37975,159,202 - 75,193,478 (+)NCBIGRCm37mm9NCBIm37
MGSCv36975,097,304 - 75,131,580 (+)NCBImm8
Celera972,465,062 - 72,505,297 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gnb5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731986
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.