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Gene: Ascl1 (achaete-scute family bHLH transcription factor 1) Mus musculus
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Symbol: Ascl1
Name: achaete-scute family bHLH transcription factor 1
Description: Exhibits DNA-binding transcription factor activity; chromatin binding activity; and sequence-specific DNA binding activity. Involved in several processes, including musculoskeletal movement, spinal reflex action; nervous system development; and neuroendocrine cell differentiation. Localizes to the neuronal cell body and nucleus. Human ortholog(s) of this gene implicated in congenital central hypoventilation syndrome. Is expressed in several structures, including alimentary system; future brain; genitourinary system; nervous system; and sensory organ. Orthologous to human ASCL1 (achaete-scute family bHLH transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: achaete-scute complex homolog 1; achaete-scute complex homolog-like 1; achaete-scute complex-like protein 1; achaete-scute homolog 1; AI225900; ASH-1; ASH1; bHLHa46; mammalian achaete scute homolog 1; mASH-1; Mash1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381087,490,819 - 87,493,660 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371086,953,786 - 86,956,405 (-)NCBIGRCm37mm9NCBIm37
MGSCv361086,920,621 - 86,922,980 (-)NCBImm8
Celera1089,464,389 - 89,467,010 (-)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ascl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732027
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.