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Gene: NR4A2 (nuclear receptor subfamily 4 group A member 2) Homo sapiens
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Symbol: NR4A2
Name: nuclear receptor subfamily 4 group A member 2
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; glucocorticoid receptor binding activity; and protein heterodimerization activity. Involved in several processes, including negative regulation of apoptotic signaling pathway; negative regulation of transcription by RNA polymerase II; and transcription, DNA-templated. Localizes to the nuclear speck. Implicated in Parkinson's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HZF-3; immediate-early response protein NOT; intermediate-early receptor protein; NGFI-B/nur77 beta-type transcription factor homolog; NOT; nuclear receptor related 1; nuclear receptor subfamily 4, group A, member 2; nur related protein-1, human homolog of; NURR1; orphan nuclear receptor NR4A2; orphan nuclear receptor NURR1; RNR1; T-cell nuclear receptor NOT; TINUR; transcriptionally inducible nuclear receptor related 1; transcriptionally-inducible nuclear receptor
Orthologs:
Mus musculus (house mouse) : Nr4a2 (nuclear receptor subfamily 4, group A, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nr4a2 (nuclear receptor subfamily 4, group A, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr4a2 (nuclear receptor subfamily 4 group A member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NR4A2 (nuclear receptor subfamily 4 group A member 2)
Canis lupus familiaris (dog) : NR4A2 (nuclear receptor subfamily 4 group A member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr4a2 (nuclear receptor subfamily 4 group A member 2)
Sus scrofa (pig) : NR4A2 (nuclear receptor subfamily 4 group A member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382156,324,432 - 156,332,724 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372157,180,944 - 157,189,287 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362156,889,195 - 156,897,446 (-)NCBINCBI36hg18NCBI36
Build 342157,006,458 - 157,014,708NCBI
Celera2150,794,299 - 150,802,639 (-)NCBI
Cytogenetic Map2q24.1NCBI
HuRef2149,066,205 - 149,074,545 (-)NCBIHuRef
CHM1_12157,187,025 - 157,195,368 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NR4A2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732028
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.