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Gene: SLC25A5 (solute carrier family 25 member 5) Homo sapiens
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Symbol: SLC25A5
Name: solute carrier family 25 member 5
Description: This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2F1; AAC2; adenine nucleotide translocator 2 (fibroblast); ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; ADP/ATP carrier protein; ADP/ATP translocase 2; ANT 2; ANT2; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5; T2; T3
Orthologs:
Mus musculus (house mouse) : Slc25a5 (solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc25a5 (solute carrier family 25 member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc25a5 (solute carrier family 25 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC25A5 (solute carrier family 25 member 5)
Canis lupus familiaris (dog) : SLC25A5 (solute carrier family 25 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc25a5 (solute carrier family 25 member 5)
Sus scrofa (pig) : SLC25A5 (solute carrier family 25 member 5)
more info ...
Related Pseudogenes: SLC25A5P1   SLC25A5P2   SLC25A5P3   SLC25A5P4   SLC25A5P5   SLC25A5P6   SLC25A5P7   SLC25A5P8   SLC25A5P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X119,468,400 - 119,471,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X118,602,363 - 118,605,359 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,486,433 - 118,489,320 (+)NCBINCBI36hg18NCBI36
Build 34X118,384,290 - 118,387,161NCBI
CeleraX119,057,070 - 119,060,067 (+)NCBI
Cytogenetic MapXq24NCBI
HuRefX108,095,551 - 108,098,548 (+)NCBIHuRef
CHM1_1X118,513,525 - 118,516,522 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC25A5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732042
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.