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Gene: SLC25A5 (solute carrier family 25 member 5) Homo sapiens
Symbol: SLC25A5
Name: solute carrier family 25 member 5
Description: This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2F1; AAC2; adenine nucleotide translocator 2 (fibroblast); ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; ADP/ATP carrier protein; ADP/ATP translocase 2; ANT 2; ANT2; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5; T2; T3
Mus musculus (house mouse) : Slc25a5 (solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc25a5 (solute carrier family 25 member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc25a5 (solute carrier family 25 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC25A5 (solute carrier family 25 member 5)
Canis lupus familiaris (dog) : SLC25A5 (solute carrier family 25 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc25a5 (solute carrier family 25 member 5)
Sus scrofa (pig) : SLC25A5 (solute carrier family 25 member 5)
more info ...
Related Pseudogenes: SLC25A5P1   SLC25A5P2   SLC25A5P3   SLC25A5P4   SLC25A5P5   SLC25A5P6   SLC25A5P7   SLC25A5P8   SLC25A5P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X119,468,400 - 119,471,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X118,602,363 - 118,605,359 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,486,433 - 118,489,320 (+)NCBINCBI36hg18NCBI36
Build 34X118,384,290 - 118,387,161NCBI
CeleraX119,057,070 - 119,060,067 (+)NCBI
Cytogenetic MapXq24NCBI
HuRefX108,095,551 - 108,098,548 (+)NCBIHuRef
CHM1_1X118,513,525 - 118,516,522 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC25A5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732042
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.