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Gene: CHN1 (chimerin 1) Homo sapiens
Symbol: CHN1
Name: chimerin 1
Description: Predicted to have GTPase activator activity and ephrin receptor binding activity. Predicted to be involved in ephrin receptor signaling pathway; generation of neurons; and regulation of GTPase activity. Predicted to localize to cytosol. Implicated in Duane retraction syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A-chimaerin; a2-chimaerin; alpha-chimerin; ARHGAP2; chimaerin 1; chimerin (chimaerin) 1; CHN; Duane retraction syndrome 2; DURS2; N-chimaerin; n-chimerin; NC; Rho GTPase-activating protein 2; RHOGAP2
Mus musculus (house mouse) : Chn1 (chimerin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chn1 (chimerin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chn1 (chimerin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CHN1 (chimerin 1)
Canis lupus familiaris (dog) : CHN1 (chimerin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chn1 (chimerin 1)
Sus scrofa (pig) : CHN1 (chimerin 1)
Chlorocebus sabaeus (African green monkey) : CHN1 (chimerin 1)
Heterocephalus glaber (naked mole-rat) : Chn1 (chimerin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2174,799,313 - 175,005,381 (-)EnsemblGRCh38hg38GRCh38
GRCh382174,798,809 - 175,005,381 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372175,664,042 - 175,870,671 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362175,372,338 - 175,578,361 (-)NCBINCBI36hg18NCBI36
Build 342175,489,740 - 175,695,461NCBI
Celera2169,277,589 - 169,483,716 (-)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2167,544,975 - 167,750,776 (-)NCBIHuRef
CHM1_12175,670,072 - 175,876,103 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHN1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732086
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.