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![]() Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | RGD:732116 | 6480464 | 2 more ... | CTD | PMID:25639565 | 2,2',4,4'-Tetrabromodiphenyl ether | multiple interactions | ISO | RGD:732116 | 6480464 | troxerutin inhibits the reaction [2 more ... | CTD | PMID:25639565 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:732116 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PSMB7 mRNA | CTD | PMID:21570461 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | RGD:621093 | 6480464 | 2 more ... | CTD | PMID:19954255 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | RGD:621093 | 6480464 | 2 more ... | CTD | PMID:19954255 | 3-methylcholanthrene | increases expression | ISO | RGD:732116 | 6480464 | Methylcholanthrene results in increased expression of PSMB7 protein | CTD | PMID:16723119 | 3H-1,2-dithiole-3-thione | increases expression | ISO | RGD:732116 | 6480464 | 1, 2-dithiol-3-thione results in increased expression of PSMB7 mRNA | CTD | PMID:22959925 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:732116 | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of PSMB7 mRNA | CTD | PMID:18648102 | acrylamide | increases expression | ISO | RGD:621093 | 6480464 | Acrylamide results in increased expression of PSMB7 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of PSMB7 gene | CTD | PMID:27153756 | ammonium chloride | affects expression | ISO | RGD:621093 | 6480464 | Ammonium Chloride affects the expression of PSMB7 mRNA | CTD | PMID:16483693 | benzo[a]pyrene | increases expression | ISO | RGD:732116 | 6480464 | Benzo(a)pyrene results in increased expression of PSMB7 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of PSMB7 intron | CTD | PMID:30157460 | bisphenol A | increases expression | ISO | RGD:621093 | 6480464 | bisphenol A results in increased expression of PSMB7 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PSMB7 mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | ISO | RGD:621093 | 6480464 | bisphenol A results in increased methylation of PSMB7 gene | CTD | PMID:28505145 | cadmium dichloride | decreases methylation | ISO | RGD:621093 | 6480464 | Cadmium Chloride results in decreased methylation of PSMB7 promoter | CTD | PMID:22457795 | carbon nanotube | increases expression | ISO | RGD:732116 | 6480464 | Nanotubes, Carbon analog results in increased expression of PSMB7 mRNA, Nanotubes, Carbon results in increased expression of PSMB7 mRNA | CTD | PMID:25554681 | chloropicrin | affects expression | EXP | | 6480464 | chloropicrin affects the expression of PSMB7 mRNA | CTD | PMID:26352163 | choline | multiple interactions | ISO | RGD:732116 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PSMB7 gene | CTD | PMID:20938992 | clobetasol | increases expression | ISO | RGD:732116 | 6480464 | Clobetasol results in increased expression of PSMB7 mRNA | CTD | PMID:27462272 | clofibrate | increases expression | ISO | RGD:621093 | 6480464 | Clofibrate results in increased expression of PSMB7 protein | CTD | PMID:16470657 | clofibrate | increases expression | ISO | RGD:732116 | 6480464 | Clofibrate results in increased expression of PSMB7 mRNA | CTD | PMID:17585979 | clofibrate | multiple interactions | ISO | RGD:732116 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of PSMB7 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PSMB7 mRNA] | CTD | PMID:17585979 | clofibric acid | affects expression | ISO | RGD:621093 | 6480464 | Clofibric Acid affects the expression of PSMB7 mRNA | CTD | PMID:17602206 | cobalt dichloride | increases expression | ISO | RGD:621093 | 6480464 | cobaltous chloride results in increased expression of PSMB7 mRNA | CTD | PMID:24386269 | cocaine | decreases expression | ISO | RGD:621093 | 6480464 | Cocaine results in decreased expression of PSMB7 protein | CTD | PMID:25100957 | copper(II) chloride | increases expression | EXP | | 6480464 | cupric chloride results in increased expression of PSMB7 mRNA | CTD | PMID:17211630 | copper(II) sulfate | increases expression | EXP | | 6480464 | Copper Sulfate results in increased expression of PSMB7 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | RGD:732116 | 6480464 | Cyclosporine results in increased expression of PSMB7 mRNA, Cyclosporine results in increased expression of PSMB7 protein | CTD | PMID:23308384, PMID:25047351 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of PSMB7 mRNA | CTD | PMID:27989131 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of PSMB7 mRNA | CTD | PMID:20106945 | dicrotophos | decreases expression | EXP | | 6480464 | dicrotophos results in decreased expression of PSMB7 mRNA | CTD | PMID:28302478 | disodium selenite | increases expression | EXP | | 6480464 | Sodium Selenite results in increased expression of PSMB7 mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PSMB7 mRNA | CTD | PMID:27188386 | doxorubicin | increases metabolic processing | EXP | | 6480464 | Doxorubicin results in increased metabolism of PSMB7 protein | CTD | PMID:17346995 | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of PSMB7 mRNA | CTD | PMID:29803840 | finasteride | increases expression | ISO | RGD:621093 | 6480464 | Finasteride results in increased expression of PSMB7 mRNA | CTD | PMID:24136188 | flutamide | increases expression | ISO | RGD:621093 | 6480464 | Flutamide results in increased expression of PSMB7 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:732116 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PSMB7 gene | CTD | PMID:20938992 | heparin | decreases expression | EXP | | 6480464 | Heparin analog results in decreased expression of PSMB7 mRNA | CTD | PMID:26476401 | L-methionine | multiple interactions | ISO | RGD:732116 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PSMB7 gene | CTD | PMID:20938992 | lead diacetate | decreases expression | ISO | RGD:732116 | 6480464 | lead acetate results in decreased expression of PSMB7 mRNA | CTD | PMID:21829687 | lead(0) | affects splicing | EXP | | 6480464 | Lead affects the splicing of PSMB7 mRNA | CTD | PMID:28903495 | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of PSMB7 mRNA | CTD | PMID:28903495 | lead(2+) | affects splicing | EXP | | 6480464 | Lead affects the splicing of PSMB7 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | EXP | | 6480464 | Lead affects the expression of PSMB7 mRNA | CTD | PMID:28903495 | nefazodone | increases expression | ISO | RGD:621093 | 6480464 | nefazodone results in increased expression of PSMB7 mRNA | CTD | PMID:24136188 | nickel atom | multiple interactions | ISO | RGD:732116 | 6480464 | MT1 affects the reaction [Nickel affects the expression of PSMB7 mRNA], MT2 affects the reaction [Nickel affects the expression of PSMB7 mRNA] | CTD | PMID:16166738 | nimesulide | increases expression | ISO | RGD:621093 | 6480464 | nimesulide results in increased expression of PSMB7 mRNA | CTD | PMID:24136188 | paracetamol | multiple interactions | ISO | RGD:732116 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of PSMB7 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PSMB7 mRNA] | CTD | PMID:17585979 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PSMB7 mRNA | CTD | PMID:21420995 | paracetamol | increases expression | ISO | RGD:621093 | 6480464 | Acetaminophen results in increased expression of PSMB7 mRNA, Acetaminophen results in increased expression of PSMB7 protein | CTD | PMID:15800402 | perfluorooctane-1-sulfonic acid | affects expression | ISO | RGD:732116 | 6480464 | perfluorooctane sulfonic acid affects the expression of PSMB7 mRNA | CTD | PMID:19429403 | perfluorooctane-1-sulfonic acid | increases expression | ISO | RGD:732116 | 6480464 | perfluorooctane sulfonic acid results in increased expression of PSMB7 mRNA | CTD | PMID:20936131 | perfluorooctanoic acid | affects expression | ISO | RGD:732116 | 6480464 | perfluorooctanoic acid affects the expression of PSMB7 mRNA | CTD | PMID:19429403 | phenobarbital | affects expression | ISO | RGD:732116 | 6480464 | Phenobarbital affects the expression of PSMB7 mRNA | CTD | PMID:23091169 | piperonyl butoxide | increases expression | ISO | RGD:621093 | 6480464 | Piperonyl Butoxide results in increased expression of PSMB7 mRNA | CTD | PMID:22484513 | pirinixic acid | increases expression | ISO | RGD:732116 | 6480464 | pirinixic acid results in increased expression of PSMB7 mRNA | CTD | PMID:15375163, PMID:23811191 | resveratrol | decreases expression | ISO | RGD:732116 | 6480464 | resveratrol results in decreased expression of PSMB7 protein | CTD | PMID:25505154 | Salinomycin | decreases expression | EXP | | 6480464 | salinomycin results in decreased expression of PSMB7 mRNA | CTD | PMID:19682730 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PSMB7 mRNA | CTD | PMID:27188386 | stattic | decreases expression | EXP | | 6480464 | stattic results in decreased expression of PSMB7 mRNA, stattic results in decreased expression of PSMB7 protein | CTD | PMID:24627483 | T-2 Toxin | affects expression | ISO | RGD:621093 | 6480464 | T-2 Toxin affects the expression of PSMB7 protein | CTD | PMID:26141394 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of PSMB7 mRNA | CTD | PMID:24935251 | trimellitic anhydride | increases expression | ISO | RGD:732116 | 6480464 | trimellitic anhydride results in increased expression of PSMB7 mRNA | CTD | PMID:19042947 | tungsten | increases expression | ISO | RGD:732116 | 6480464 | Tungsten results in increased expression of PSMB7 mRNA | CTD | PMID:30912803 | valdecoxib | increases expression | ISO | RGD:621093 | 6480464 | valdecoxib results in increased expression of PSMB7 mRNA | CTD | PMID:24136188 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of PSMB7 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PSMB7 mRNA | CTD | PMID:27188386 | |
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1. | GOA_HUMAN data from the GO Consortium |
2. | Pipeline to import KEGG annotations from KEGG into RGD |
3. | RGD automated import pipeline for gene-chemical interactions |
PubMed | 7811265 8125298 8666937 8811196 9079628 9311996 9811770 9846577 10384092 10893419 11205743 11285280 11295498 11745344 12167863 12376572 12419264 12477932 12719574 12750511 12791267 12808465 12808466 12809610 12830140 12840737 12859895 12914693 12920286 12970355 14527406 14528300 14528301 14550573 14557625 14564014 14614829 14702039 14733938 15029244 15489334 15592455 15887188 16169070 16196087 16423992 16611982 17323924 17573772 17948026 18378283 18462727 18549262 18768472 18922472 19193609 19645816 20010949 20379614 20723761 20736409 21139048 21565611 21630459 21713324 21726808 21853274 21873635 21890473 21906983 21963094 21987572 21988832 22118674 22119785 22505724 22645313 22863883 22939629 23000965 23275563 23376485 23438482 23443559 23503661 24163370 24270810 24816145 25147182 26186194 26344197 26496610 27428775 27705803 28077445 28137758 28276505 28292943 28514442 28548215 28581483 28685749 28821611 29053956 29117863 29229926 29426014 29507755 29568061 29666234 29911972 30033366 30257870 30425250 30833792 |
PSMB7 (Homo sapiens - human) |
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Psmb7 (Mus musculus - house mouse) |
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Psmb7 (Rattus norvegicus - Norway rat) |
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Psmb7 (Chinchilla lanigera - long-tailed chinchilla) |
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PSMB7 (Pan paniscus - bonobo/pygmy chimpanzee) |
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PSMB7 (Canis lupus familiaris - dog) |
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Psmb7 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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PSMB7 (Sus scrofa - pig) |
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RH77983 |
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Cda0vc07 |
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D9S1698 |
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SGC33089 |
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RH119892 |
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D9S997E |
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SHGC-154753 |
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A003A40 |
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RH11482 |
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RH70504 |
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D9S1989 |
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RH11599 |
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RH12239 |
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G20648 |
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A006A17 |
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WI-15624 |
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MARC_8227-8228:996688432:1 |
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The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
RefSeq Transcripts | NM_002799 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
GenBank Nucleotide | AJ420455 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AK056654 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK098757 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK223007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK223356 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK303460 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK308756 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK314302 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AL137846 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC000509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC008414 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC017116 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BT007218 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH471090 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CR456721 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
D38048 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GQ891532 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GU727627 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
U44425 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | NM_002799 ⟹ NP_002790 | |||||||||||||||||||||||||||||
RefSeq Status: | REVIEWED | |||||||||||||||||||||||||||||
Type: | CODING | |||||||||||||||||||||||||||||
Position: |
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Sequence: |
TCTTTTTGTTTGCACCCGCCTCCGACCCGGAACTGCTTTCTTGGGAAGATGGCGGCTGTGTCGGhide sequence |
Protein RefSeqs | NP_002790 | (Get FASTA) | NCBI Sequence Viewer |
GenBank Protein | AAD45962 | (Get FASTA) | NCBI Sequence Viewer |
AAH00509 | (Get FASTA) | NCBI Sequence Viewer | |
AAH17116 | (Get FASTA) | NCBI Sequence Viewer | |
AAP35882 | (Get FASTA) | NCBI Sequence Viewer | |
ADO22394 | (Get FASTA) | NCBI Sequence Viewer | |
ADU87629 | (Get FASTA) | NCBI Sequence Viewer | |
BAA07238 | (Get FASTA) | NCBI Sequence Viewer | |
BAD96727 | (Get FASTA) | NCBI Sequence Viewer | |
BAD97076 | (Get FASTA) | NCBI Sequence Viewer | |
BAG36956 | (Get FASTA) | NCBI Sequence Viewer | |
BAG64503 | (Get FASTA) | NCBI Sequence Viewer | |
CAG33002 | (Get FASTA) | NCBI Sequence Viewer | |
EAW87582 | (Get FASTA) | NCBI Sequence Viewer | |
EAW87583 | (Get FASTA) | NCBI Sequence Viewer | |
Q99436 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_002790 ⟸ NM_002799 |
- Peptide Label: | precursor |
- UniProtKB: | Q99436 (UniProtKB/Swiss-Prot), E9KL30 (UniProtKB/TrEMBL) |
- Sequence: |
MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRAThide sequence |
RGD ID: | 7216113 | |||||||||
Promoter ID: | EPDNEW_H13803 | |||||||||
Type: | initiation region | |||||||||
Name: | PSMB7_1 | |||||||||
Description: | proteasome subunit beta 7 | |||||||||
SO ACC ID: | SO:0000170 | |||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
Experiment Methods: | Single-end sequencing. | |||||||||
Position: |
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RGD ID: | 6807993 | |||||||||
Promoter ID: | HG_KWN:64888 | |||||||||
Type: | CpG-Island | |||||||||
SO ACC ID: | SO:0000170 | |||||||||
Source: | MPROMDB | |||||||||
Tissues & Cell Lines: | CD4+TCell, CD4+TCell_12Hour, HeLa_S3, K562, Lymphoblastoid, NB4 | |||||||||
Transcripts: | NM_002799, OTTHUMT00000055526, OTTHUMT00000055527, OTTHUMT00000055530, UC010MWM.1 | |||||||||
Position: |
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RGD ID: | 6851820 | |||||||||
Promoter ID: | EP73715 | |||||||||
Type: | multiple initiation site | |||||||||
Name: | HS_PSMB7 | |||||||||
Description: | Proteasome (prosome, macropain) subunit, beta type, 7. | |||||||||
SO ACC ID: | SO:0000170 | |||||||||
Source: | EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
Experiment Methods: | NEDO full length human cDNA sequencing project.; Oligo-capping | |||||||||
Position: |
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Name | Type | Condition(s) | Position(s) | Clinical significance |
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 | copy number gain | Global developmental delay [RCV000050347]|Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000050348]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000050348]|See cases [RCV000050348] | Chr9:193412..138179445 [GRCh38] Chr9:204193..141073897 [GRCh37] Chr9:194193..140193718 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh38/hg38 9q33.2-34.3(chr9:122792658-138124532)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051040]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051040]|See cases [RCV000051040] | Chr9:122792658..138124532 [GRCh38] Chr9:125554937..141018984 [GRCh37] Chr9:124594758..140138805 [NCBI36] Chr9:9q33.2-34.3 |
pathogenic |
GRCh38/hg38 9q33.2-34.3(chr9:121112395-138075224)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051009]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051009]|See cases [RCV000051009] | Chr9:121112395..138075224 [GRCh38] Chr9:123874673..140969676 [GRCh37] Chr9:122914494..140089497 [NCBI36] Chr9:9q33.2-34.3 |
pathogenic |
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124532)x3 | copy number gain | Intrauterine growth retardation [RCV000053745]|See cases [RCV000053745] | Chr9:193412..138124532 [GRCh38] Chr9:204193..141018984 [GRCh37] Chr9:194193..140138805 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|See cases [RCV000053748] | Chr9:193412..138179445 [GRCh38] Chr9:266045..141073897 [GRCh37] Chr9:256045..140193718 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh38/hg38 9q33.2-34.3(chr9:121586837-138179445)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053776]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053776]|See cases [RCV000053776] | Chr9:121586837..138179445 [GRCh38] Chr9:124349116..141073897 [GRCh37] Chr9:123388937..140193718 [NCBI36] Chr9:9q33.2-34.3 |
pathogenic |
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138114463)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053746]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053746]|See cases [RCV000053746] | Chr9:193412..138114463 [GRCh38] Chr9:214367..141008915 [GRCh37] Chr9:204367..140128736 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh38/hg38 9p24.3-q34.3(chr9:204193-138179445) | copy number gain | See cases [RCV000133791] | Chr9:204193..138179445 [GRCh38] Chr9:204193..141073897 [GRCh37] Chr9:194193..140193718 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh38/hg38 9q33.2-34.3(chr9:121073102-138179445)x3 | copy number gain | See cases [RCV000134920] | Chr9:121073102..138179445 [GRCh38] Chr9:123835380..141073897 [GRCh37] Chr9:122875201..140193718 [NCBI36] Chr9:9q33.2-34.3 |
pathogenic |
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124524)x3 | copy number gain | See cases [RCV000138783] | Chr9:193412..138124524 [GRCh38] Chr9:204090..141018976 [GRCh37] Chr9:194090..140138797 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh38/hg38 9p11.2-q34.3(chr9:193412-138159073)x3 | copy number gain | See cases [RCV000139207] | Chr9:193412..138159073 [GRCh38] Chr9:68420641..141053525 [GRCh37] Chr9:67910461..140173346 [NCBI36] Chr9:9p11.2-q34.3 |
pathogenic |
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138159073)x3 | copy number gain | See cases [RCV000138962] | Chr9:193412..138159073 [GRCh38] Chr9:204104..141053525 [GRCh37] Chr9:194104..140173346 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic|conflicting data from submitters |
GRCh38/hg38 9p24.3-q34.3(chr9:203861-138125937)x3 | copy number gain | See cases [RCV000141876] | Chr9:203861..138125937 [GRCh38] Chr9:203861..141020389 [GRCh37] Chr9:193861..140140210 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh38/hg38 9q33.2-33.3(chr9:123095598-126693843)x1 | copy number loss | See cases [RCV000141589] | Chr9:123095598..126693843 [GRCh38] Chr9:125857877..129456122 [GRCh37] Chr9:124897698..128495943 [NCBI36] Chr9:9q33.2-33.3 |
pathogenic |
GRCh38/hg38 9p24.3-q34.3(chr9:203862-138125937)x3 | copy number gain | See cases [RCV000143476] | Chr9:203862..138125937 [GRCh38] Chr9:203862..141020389 [GRCh37] Chr9:193862..140140210 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 | copy number gain | See cases [RCV000148113] | Chr9:193412..138179445 [GRCh38] Chr9:204193..141073897 [GRCh37] Chr9:194193..140193718 [NCBI36] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:163131-141122114)x3 | copy number gain | See cases [RCV000240081] | Chr9:163131..141122114 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:62525-141006407) | copy number gain | See cases [RCV000449375] | Chr9:62525..141006407 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:203861-141020389)x3 | copy number gain | See cases [RCV000447207] | Chr9:203861..141020389 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9q33.2-34.3(chr9:124642754-141146461)x3 | copy number gain | See cases [RCV000448784] | Chr9:124642754..141146461 [GRCh37] Chr9:9q33.2-34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:203864-141020389)x3 | copy number gain | See cases [RCV000448978] | Chr9:203864..141020389 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9q21.11-34.3(chr9:71069743-140999928) | copy number gain | Global developmental delay [RCV000626548]|Seizures [RCV000626548] | Chr9:71069743..140999928 [GRCh37] Chr9:9q21.11-34.3 |
likely pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:203862-141020389) | copy number gain | See cases [RCV000512392] | Chr9:203862..141020389 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141122247)x3 | copy number gain | not provided [RCV000748055] | Chr9:10590..141122247 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141107672)x3 | copy number gain | not provided [RCV000748053] | Chr9:10590..141107672 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:46587-141066491)x3 | copy number gain | not provided [RCV000748063] | Chr9:46587..141066491 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141114095)x2 | copy number gain | not provided [RCV000748054] | Chr9:10590..141114095 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9p24.3-q34.3(chr9:203861-141020388)x3 | copy number gain | not provided [RCV000845900] | Chr9:203861..141020388 [GRCh37] Chr9:9p24.3-q34.3 |
pathogenic |
GRCh37/hg19 9q21.11-34.3(chr9:71416475-141020389)x3 | copy number gain | not provided [RCV000847808] | Chr9:71416475..141020389 [GRCh37] Chr9:9q21.11-34.3 |
pathogenic |
Database | Acc Id | Source(s) |
AGR Gene | HGNC:9544 | AgrOrtholog |
COSMIC | PSMB7 | COSMIC |
Ensembl Genes | ENSG00000136930 | ENTREZGENE, UniProtKB/Swiss-Prot |
Ensembl Protein | ENSP00000259457 | ENTREZGENE, UniProtKB/Swiss-Prot |
ENSP00000393157 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENST00000259457 | ENTREZGENE, UniProtKB/Swiss-Prot |
ENST00000441097 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.60.20.10 | UniProtKB/Swiss-Prot |
GTEx | ENSG00000136930 | GTEx |
HGNC ID | HGNC:9544 | ENTREZGENE |
Human Proteome Map | PSMB7 | Human Proteome Map |
InterPro | Ntn_hydrolases_N | UniProtKB/Swiss-Prot |
Pept_T1A_subB | UniProtKB/Swiss-Prot | |
Proteasome_beta7 | UniProtKB/Swiss-Prot | |
Proteasome_bsu_C | UniProtKB/Swiss-Prot | |
Proteasome_bsu_CS | UniProtKB/Swiss-Prot | |
Proteasome_sua/b | UniProtKB/Swiss-Prot | |
Proteasome_suB-type | UniProtKB/Swiss-Prot | |
KEGG Report | hsa:5695 | UniProtKB/Swiss-Prot |
NCBI Gene | 5695 | ENTREZGENE |
OMIM | 604030 | OMIM |
PANTHER | PTHR11599:SF42 | UniProtKB/Swiss-Prot |
Pfam | Pr_beta_C | UniProtKB/Swiss-Prot |
Proteasome | UniProtKB/Swiss-Prot | |
PharmGKB | PA33889 | PharmGKB |
PRINTS | PROTEASOME | UniProtKB/Swiss-Prot |
PROSITE | PROTEASOME_BETA_1 | UniProtKB/Swiss-Prot |
PROTEASOME_BETA_2 | UniProtKB/Swiss-Prot | |
Superfamily-SCOP | SSF56235 | UniProtKB/Swiss-Prot |
UniGene | Hs.213470 | ENTREZGENE |
UniProt | E9KL30 | ENTREZGENE, UniProtKB/TrEMBL |
PSB7_HUMAN | UniProtKB/Swiss-Prot | |
Q5TBG5_HUMAN | UniProtKB/TrEMBL | |
Q6IBT1_HUMAN | UniProtKB/TrEMBL | |
Q99436 | ENTREZGENE | |
UniProt Secondary | B4E0P1 | UniProtKB/Swiss-Prot |
Q5TBG6 | UniProtKB/Swiss-Prot | |
Q96AG8 | UniProtKB/Swiss-Prot | |
Q9BWA7 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2019-09-03 | PSMB7 | proteasome 20S subunit beta 7 | PSMB7 | proteasome subunit beta 7 | Symbol and/or name change | 5135510 | APPROVED |
2015-08-18 | PSMB7 | proteasome subunit beta 7 | proteasome (prosome, macropain) subunit, beta type, 7 | Symbol and/or name change | 5135510 | APPROVED |
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More on PSMB7 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: hg19 hg38 |
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HGNC Report |
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NCBI Genome Data Viewer |
CRRD Object Information | |
CRRD ID: | 732115 |
Created: | 2004-01-12 |
Species: | Homo sapiens |
Last Modified: | 2019-11-26 |
Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.