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Gene: SLC1A3 (solute carrier family 1 member 3) Homo sapiens
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Symbol: SLC1A3
Name: solute carrier family 1 member 3
Description: Exhibits high-affinity glutamate transmembrane transporter activity. Involved in amino acid import across plasma membrane and inorganic ion transmembrane transport. Localizes to the integral component of plasma membrane. Implicated in episodic ataxia type 6.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EA6; EAAT1; excitatory amino acid transporter 1; FLJ25094; GLAST; GLAST-1; GLAST1; sodium-dependent glutamate/aspartate transporter 1; solute carrier family 1 (glial high affinity glutamate transporter), member 3; solute carrier family 1, member 3
Orthologs:
Mus musculus (house mouse) : Slc1a3 (solute carrier family 1 (glial high affinity glutamate transporter), member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc1a3 (solute carrier family 1 member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc1a3 (solute carrier family 1 member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC1A3 (solute carrier family 1 member 3)
Canis lupus familiaris (dog) : SLC1A3 (solute carrier family 1 member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc1a3 (solute carrier family 1 member 3)
Sus scrofa (pig) : SLC1A3 (solute carrier family 1 member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38536,606,355 - 36,688,334 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37536,606,457 - 36,688,436 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36536,642,446 - 36,724,191 (+)NCBINCBI36hg18NCBI36
Build 34536,642,447 - 36,724,197NCBI
Celera536,493,385 - 36,575,353 (+)NCBI
Cytogenetic Map5p13.2NCBI
HuRef536,559,517 - 36,641,481 (+)NCBIHuRef
CHM1_1536,609,230 - 36,691,155 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC1A3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732126
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.