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Gene: RGN (regucalcin) Homo sapiens
Symbol: RGN
Name: regucalcin
Description: The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: epididymis secretory protein Li 41; gluconolactonase; GNL; HEL-S-41; RC; senescence marker protein 30; senescence marker protein-30; SMP-30; SMP30
Mus musculus (house mouse) : Rgn (regucalcin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rgn (regucalcin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgn (regucalcin)
Pan paniscus (bonobo/pygmy chimpanzee) : RGN (regucalcin)
Canis lupus familiaris (dog) : RGN (regucalcin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgn (regucalcin)
Sus scrofa (pig) : RGN (regucalcin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X47,078,355 - 47,093,314 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X46,937,775 - 46,952,712 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X46,822,719 - 46,837,656 (+)NCBINCBI36hg18NCBI36
Build 34X46,696,510 - 46,708,966NCBI
CeleraX51,129,720 - 51,148,035 (+)NCBI
Cytogenetic MapXp11.3NCBI
HuRefX44,651,176 - 44,667,384 (+)NCBIHuRef
CHM1_1X46,969,543 - 46,984,508 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RGN
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732128
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.