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Gene: P3h1 (prolyl 3-hydroxylase 1) Mus musculus
Symbol: P3h1
Name: prolyl 3-hydroxylase 1
CRRD ID: 732133
Description: Predicted to have procollagen-proline 3-dioxygenase activity. Involved in collagen fibril organization; negative regulation of cell growth; and regulation of ossification. Predicted to localize to basement membrane; endoplasmic reticulum; and nucleus. Is expressed in several structures, including branchial arch; limb; lower jaw; sensory organ; and skeleton. Used to study osteogenesis imperfecta type 8. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 8. Orthologous to human P3H1 (prolyl 3-hydroxylase 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410024C15Rik; Gr; Gros1; growth suppressor 1; growth supressor 1; Lep; Lepre1; leprecan 1; leprecan-1; leucine- and proline-enriched proteoglycan 1
Homo sapiens (human) : P3H1 (prolyl 3-hydroxylase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : P3h1 (prolyl 3-hydroxylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P3h1 (prolyl 3-hydroxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : P3H1 (prolyl 3-hydroxylase 1)
Canis lupus familiaris (dog) : P3H1 (prolyl 3-hydroxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P3h1 (prolyl 3-hydroxylase 1)
Sus scrofa (pig) : P3H1 (prolyl 3-hydroxylase 1)
Chlorocebus sabaeus (African green monkey) : P3H1 (prolyl 3-hydroxylase 1)
Heterocephalus glaber (naked mole-rat) : P3h1 (prolyl 3-hydroxylase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm394119,090,112 - 119,106,174 (+)NCBI
GRCm384119,232,915 - 119,248,977 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4119,232,915 - 119,248,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv374118,905,520 - 118,921,582 (+)NCBIGRCm37mm9NCBIm37
MGSCv364118,730,878 - 118,746,299 (+)NCBImm8
Celera4117,960,655 - 117,976,715 (+)NCBICelera
Cytogenetic Map4D2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on P3h1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732133
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.