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Gene: Il12a (interleukin 12a) Mus musculus
Symbol: Il12a
Name: interleukin 12a
Description: Exhibits interleukin-12 beta subunit binding activity. Contributes to cytokine activity. Involved in several processes, including T-helper 1 cell activation; T-helper 1 cell cytokine production; and positive regulation of T cell activation. Localizes to the cell surface; cytoplasm; and interleukin-12 complex. Orthologous to human IL12A (interleukin 12A); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-27 signaling pathway; allograft rejection pathway; INTERACTS WITH (S)-nicotine; 1-chloro-2,4-dinitrobenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CLMF p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 p35 subunit; IL-12 subunit p35; Il-12a; IL-12p35; interleukin 12a p35 subunit; interleukin-12 p35 subunit; interleukin-12 subunit alpha; Ll12a; MGC151228; MGC151232; p35
Homo sapiens (human) : IL12A (interleukin 12A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il12a (interleukin 12A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il12a (interleukin 12A)
Pan paniscus (bonobo/pygmy chimpanzee) : IL12A (interleukin 12A)
Canis lupus familiaris (dog) : IL12A (interleukin 12A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il12a (interleukin 12A)
Sus scrofa (pig) : IL12A (interleukin 12A)
Chlorocebus sabaeus (green monkey) : IL12A (interleukin 12A)
Heterocephalus glaber (naked mole-rat) : Il12a (interleukin 12A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl368,690,644 - 68,698,547 (+)Ensembl
GRCm38368,690,644 - 68,698,550 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37368,494,566 - 68,502,469 (+)NCBIGRCm37mm9NCBIm37
MGSCv36368,778,573 - 68,786,454 (+)NCBImm8
Celera368,820,603 - 68,828,509 (+)NCBICelera
Cytogenetic Map3 E1NCBI
cM Map331.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il12a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732140
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.