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Gene: Il12a (interleukin 12a) Mus musculus
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Symbol: Il12a
Name: interleukin 12a
Description: Exhibits interleukin-12 beta subunit binding activity. Contributes to cytokine activity. Involved in several processes, including T-helper 1 cell activation; T-helper 1 cell cytokine production; and positive regulation of T cell activation. Localizes to the cell surface; cytoplasm; and interleukin-12 complex. Orthologous to human IL12A (interleukin 12A); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-27 signaling pathway; allograft rejection pathway; INTERACTS WITH (S)-nicotine; 1-chloro-2,4-dinitrobenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CLMF p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 p35 subunit; IL-12 subunit p35; Il-12a; IL-12p35; interleukin 12a p35 subunit; interleukin-12 p35 subunit; interleukin-12 subunit alpha; Ll12a; MGC151228; MGC151232; p35
Orthologs:
Homo sapiens (human) : IL12A (interleukin 12A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il12a (interleukin 12A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il12a (interleukin 12A)
Pan paniscus (bonobo/pygmy chimpanzee) : IL12A (interleukin 12A)
Canis lupus familiaris (dog) : IL12A (interleukin 12A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il12a (interleukin 12A)
Sus scrofa (pig) : IL12A (interleukin 12A)
Chlorocebus sabaeus (green monkey) : IL12A (interleukin 12A)
Heterocephalus glaber (naked mole-rat) : Il12a (interleukin 12A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl368,690,644 - 68,698,547 (+)Ensembl
GRCm38368,690,644 - 68,698,550 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37368,494,566 - 68,502,469 (+)NCBIGRCm37mm9NCBIm37
MGSCv36368,778,573 - 68,786,454 (+)NCBImm8
Celera368,820,603 - 68,828,509 (+)NCBICelera
Cytogenetic Map3 E1NCBI
cM Map331.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Il12a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732140
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.