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Gene: Txnip (thioredoxin interacting protein) Mus musculus
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Symbol: Txnip
Name: thioredoxin interacting protein
Description: Exhibits enzyme inhibitor activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; platelet-derived growth factor receptor signaling pathway; and protein import into nucleus. Localizes to the cytoplasm. Used to study Reye syndrome and hepatocellular carcinoma. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human TXNIP (thioredoxin interacting protein); INTERACTS WITH (-)-anisomycin; (S)-nicotine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1200008J08Rik; AA682105; hyperlipidemia 1; Hyplip1; Tbp-2; THIF; thioredoxin binding protein-2; thioredoxin-interacting protein; upregulated by 1,25-dihydroxyvitamin D-3; VDUP1; vitamin D3 up-regulated protein 1
Orthologs:
Homo sapiens (human) : TXNIP (thioredoxin interacting protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Txnip (thioredoxin interacting protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txnip (thioredoxin interacting protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TXNIP (thioredoxin interacting protein)
Canis lupus familiaris (dog) : TXNIP (thioredoxin interacting protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txnip (thioredoxin interacting protein)
Sus scrofa (pig) : TXNIP (thioredoxin interacting protein)
Chlorocebus sabaeus (African green monkey) : TXNIP (thioredoxin interacting protein)
Heterocephalus glaber (naked mole-rat) : Txnip (thioredoxin interacting protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl396,557,957 - 96,561,883 (+)EnsemblGRCm38mm10GRCm38
GRCm38396,557,957 - 96,561,857 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37396,361,880 - 96,365,780 (+)NCBIGRCm37mm9NCBIm37
MGSCv36396,643,362 - 96,647,271 (+)NCBImm8
Celera397,964,967 - 97,968,875 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map341.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Txnip
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732141
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.