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Gene: PDCD4 (programmed cell death 4) Homo sapiens
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Symbol: PDCD4
Name: programmed cell death 4
Description: Predicted to have RNA binding activity. Involved in several processes, including negative regulation of cell differentiation; positive regulation of apoptotic process; and regulation of transcription, DNA-templated. Localizes to the cytosol and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H731; MGC33046; MGC33047; neoplastic transformation inhibitor protein; nuclear antigen H731; nuclear antigen H731-like; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a
Orthologs:
Mus musculus (house mouse) : Pdcd4 (programmed cell death 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdcd4 (programmed cell death 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdcd4 (programmed cell death 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PDCD4 (programmed cell death 4)
Canis lupus familiaris (dog) : PDCD4 (programmed cell death 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdcd4 (programmed cell death 4)
Sus scrofa (pig) : PDCD4 (programmed cell death 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810110,871,795 - 110,900,006 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710112,631,553 - 112,659,764 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610112,621,586 - 112,649,754 (+)NCBINCBI36hg18NCBI36
Build 3410112,621,585 - 112,649,753NCBI
Celera10106,363,204 - 106,391,372 (+)NCBI
Cytogenetic Map10q25.2NCBI
HuRef10106,260,410 - 106,288,621 (+)NCBIHuRef
CHM1_110112,913,378 - 112,941,587 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PDCD4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732159
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.