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Gene: PDCD4 (programmed cell death 4) Homo sapiens
Symbol: PDCD4
Name: programmed cell death 4
CRRD ID: 732159
Description: Predicted to have RNA binding activity. Involved in several processes, including negative regulation of cell differentiation; negative regulation of vascular associated smooth muscle cell proliferation; and positive regulation of apoptotic process. Localizes to cytosol and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H731; MGC33046; MGC33047; neoplastic transformation inhibitor protein; nuclear antigen H731; nuclear antigen H731-like; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a
Mus musculus (house mouse) : Pdcd4 (programmed cell death 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdcd4 (programmed cell death 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdcd4 (programmed cell death 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PDCD4 (programmed cell death 4)
Canis lupus familiaris (dog) : PDCD4 (programmed cell death 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdcd4 (programmed cell death 4)
Sus scrofa (pig) : PDCD4 (programmed cell death 4)
Chlorocebus sabaeus (African green monkey) : PDCD4 (programmed cell death 4)
Heterocephalus glaber (naked mole-rat) : Pdcd4 (programmed cell death 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl10110,871,795 - 110,900,006 (+)EnsemblGRCh38hg38GRCh38
GRCh3810110,871,928 - 110,900,006 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710112,631,553 - 112,659,764 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610112,621,586 - 112,649,754 (+)NCBINCBI36hg18NCBI36
Build 3410112,621,585 - 112,649,753NCBI
Celera10106,363,204 - 106,391,372 (+)NCBI
Cytogenetic Map10q25.2NCBI
HuRef10106,260,410 - 106,288,621 (+)NCBIHuRef
CHM1_110112,913,378 - 112,941,587 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PDCD4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732159
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.